Bone turnover markers in children and adolescents with environmentally determined short stature, living in the oil and gas processing region.

In conditions of intensive development of gas fields, environmental safety issues are becoming increasingly important. High rates of gas production and growth of its chemical processing have turned gas industry enterprises into a powerful source of environmental pollution, which poses a real threat to public health and contributes to an increase in morbidities and environmentally determined pathological conditions. The development of methods for the diagnosis, treatment and prevention of such conditions is an important task for modern science. The aim of the research is to make a comprehensive assessment of serum markers of bone synthesis and resorption in children with short stature living in the oil and gas processing regions. A total of 240 children aged 8-17 years, living in the oil and gas processing region (Kenkiyak), and 409 schoolchildren (8-17 years old), living in the environmentally favourable region (Kobda village), during 3 years were examined. It was established that emissions of pollutants by oil processing enterprises account for almost 80% of all emissions into the atmosphere. Gas flaring at oil production sites plays a special role in this process. Speaking of the effects of environmental factors on children's health, it should be noted that there is no consensus on the mechanisms and consequences of exposure to low doses of chemical atmospheric pollutants in children and adolescents so far.