Trial reportSurgical endoscopy2021
A three-arm randomized study to compare sexual functions and fertility indices following open mesh hernioplasty (OMH), laparoscopic totally extra peritoneal (TEP) and transabdominal preperitoneal (TAPP) repair of groin hernia.
Trial report in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04591470 (Influence of Inguinal Hernia Repair on Sperm Autoimmunity Using MAR Test), which is not on this map. Cited by 11 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Influence of Inguinal Hernia Repair on Sperm Autoimmunity Using MAR Test
Who cites it
11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Comparison of sexual function following Lichtenstein versus laparoscopic mesh repair in primary inguinal hernias, the meta-analysis of randomized controlled trials.Surgical endoscopy · 2025Pooled it
- Comparison of short- and long-term efficacy and economic indicators between transabdominal preperitoneal and open tension-free repair for inguinal hernia in adults: a meta-analysis of randomized controlled trials.Hernia : the journal of hernias and abdominal wall surgery · 2025Pooled it
- Transabdominal pre-peritoneal (TAPP) versus totally extraperitoneal (TEP) laparoscopic techniques for inguinal hernia repair.The Cochrane database of systematic reviews · 2024Pooled it
- Sexual dysfunction between laparoscopic and open inguinal hernia repair: a systematic review and meta-analysis.Langenbeck's archives of surgery · 2023Pooled it
- The effect of peri-operative pain neuroscience education on pain and recovery in adult patients receiving laparoscopic inguinal hernia repair.Scientific reports · 2025Trial
- Bilateral inguinal hernia repair and male fertility: a randomized clinical trial comparing Lichtenstein versus laparoscopic transabdominal preperitoneal (TAPP) technique.Surgical endoscopy · 2023Trial
- Operative time and recurrence across five techniques of inguinal hernia repair: a Bayesian network meta-analysis of 29 randomized trials.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- Erectile Function Before and After Elective Inguinal Hernia Repair: A Paired IIEF-5 Study Comparing Laparoscopic and Open Techniques.Journal of clinical medicine · 2026Article
- Decoding the Puzzle of Male Infertility: The Role of Infection, Inflammation, and Autoimmunity.Diagnostics (Basel, Switzerland) · 2025Review
- Laparoscopic Management of a Recurrent, Inguinal Hernia Containing Urinary Bladder: A Case Report and Literature Review.Case reports in medicine · 2025Article
- Laparoscopic transabdominal preperitoneal herniorrhaphy performed using an articulating laparoscopic instrument is feasible and more efficient.Frontiers in surgery · 2023Article
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWith evolving technology, the focus of groin hernia repair has shifted to sexual function and fertility outcomes.
methodsThis three-arm randomized study was conducted in tertiary care hospital from 1st July 2017 to 30th March 2019. Consecutive patients of groin hernia were randomized into 3 groups, TAPP (Group 1), TEP (Group 2), and OMH (Group 3). Demographic profile and hernia characteristics were assessed preoperatively. Sexual functions (using BMSFI) and fertility (using surrogate fertility indices, viz., semen analysis and anti-sperm antibodies (ASA)) were assessed preoperatively at 3 months after the surgery.
resultsA total of 121 patients were included in the study with 41 patients in TAPP (Group 1) and 40 each in TEP (Group 2) and OMH (Group3) group. All the 3 groups were comparable in terms of demographic profile, hernia characteristics, intra-operative and early post-operative outcomes. Significant improvement was found in most of the domains of BMSFI score in the study population (p value < 0.001) with no intergroup difference. There was significant increase of anti-sperm antibody level in OMH group as compared to TAPP and TEP (p = 0.001), however, the levels were within normal limit.
conclusionsIn conclusion, this study has shown that inguinal hernia repair whether open or laparoscopic (TEP or TAPP) leads on to improvement in sexual functions and fertility indices and can have a significant impact on pre-op counseling of the patient in terms of choice of repair, depending on the available expertise in a given center.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.