ArticleSurgical endoscopy2021
Benefits of linked color imaging for recognition of early differentiated-type gastric cancer: in comparison with indigo carmine contrast method and blue laser imaging.
Article in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Risk factors for missed early gastric cancer: a retrospective cohort study based on pathologically confirmed cases after endoscopic submucosal dissection.Surgical endoscopy · 2026Article
- Assessment of early gastric cancer visibility in deep-learning-based virtual indigo carmine chromoendoscopy (with video).Endoscopy international open · 2026Article
- Image-enhanced endoscopy improves visibility of endoscopic images in individuals with color vision deficiency.Endoscopy international open · 2025Article
- Diagnostic performance of deep-learning-based virtual chromoendoscopy in gastric neoplasms.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2024Article
- Global progress and future prospects of early gastric cancer screening.Journal of Cancer · 2024Review
- Clinical usefulness of linked color imaging in identifyingWorld journal of gastrointestinal endoscopy · 2023Article
- Indigo Carmine: Between Necessity and Concern.Journal of xenobiotics · 2023Review
- Vincamine, from an antioxidant and a cerebral vasodilator to its anticancer potential.Bioorganic & medicinal chemistry · 2023Review
- Clinical Usefulness of Linked Color Imaging for Detection and Characterization of UndifferentiatedType Early Gastric Cancer.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023Article
- Linked Color Imaging for Stomach.Diagnostics (Basel, Switzerland) · 2023Review
- Current status and future perspective of linked color imaging for gastric cancer screening: a literature review.Journal of gastroenterology · 2023Review
- Hereditary Diffuse Gastric Cancer: Molecular Genetics, Biological Mechanisms and Current Therapeutic Approaches.International journal of molecular sciences · 2022Review
- Traditional and Modern Diagnostic Approaches in Diagnosing PediatricChildren (Basel, Switzerland) · 2022Review
- In Living Color: Linked Color Imaging for the Detection of Early Gastric Cancer.Digestive diseases and sciences · 2022Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimLinked color imaging (LCI) is a novel endoscopy system, which enhances slight differences in mucosal color. However, whether LCI is more useful than other kinds of image-enhanced endoscopy (IEE) in recognizing early gastric cancer remains unclear. This study aimed to evaluate LCI efficacy compared with the indigo carmine contrast method (IC), and blue laser imaging-bright (BLI-brt) in early differentiated-type gastric cancer recognition.
methodsWe retrospectively analyzed early differentiated-type gastric cancer, which were examined by all four imaging techniques (white light imaging, IC, LCI, BLI-brt) at Asahi University Hospital from June 2014 to November 2018. Both subjective evaluation (using ranking score: RS) and objective evaluation (using color difference score: CDS) were adopted to quantify early differentiated-type gastric cancer recognition.
resultsDuring this period, 87 lesions were enrolled in this study. Both RS and CDS of LCI were significantly higher (p < 0.01) than those of IC and BLI-brt. Both RS and CDS of BLI-brt had no significant difference compared with those of IC. Subgroup analysis revealed that LCI was especially useful in post-Helicobacter pylori eradication patients and flat or depressed lesions compared with IC and BLI-brt.
conclusionsLCI appears to be more beneficial for the recognition of early differentiated-type gastric cancer in endoscopic screenings than IC and BLI-brt from the middle to distant view.
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