Evidence map›Paper›PMID 32556679›Full record

SynthesisNeurosurgical review2021

A review of solitary fibrous tumor/hemangiopericytoma tumor and a comparison of risk factors for recurrence, metastases, and death among patients with spinal and intracranial tumors.

Enrico Giordan, Elisabetta Marton, Alexandra M Wennberg, Angela Guerriero, Giuseppe Canova

Abstract readComparative StudyMeta-AnalysisSystematic Review
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In one paragraph

Synthesis in Neurosurgical review, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Enrico GiordanDepartment of Neurosurgery, Aulss 2 Marca Trevigiana, Via Piazzale 1, Treviso, Italy. enrico.giordan@aulss2.veneto.it.ORCID http://orcid.org/0000-0002-8863-116X
Elisabetta MartonDepartment of Neuroscience, University of Padova, Padova, Italy.
Alexandra M WennbergDepartment of Neuroscience, University of Padova and Padova Neuroscience Center, Padova, Italy.
Angela GuerrieroDepartment of Pathology, Aulss 2 Marca Trevigiana, Treviso, Italy.
Giuseppe CanovaDepartment of Neurosurgery, Aulss 2 Marca Trevigiana, Via Piazzale 1, Treviso, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Meningeal solitary fibrous tumors (SFTs) and hemangiopericytomas (HPCs) had been combined into a single classification until 2016. Recurrence and metastases rates are still understudied, especially for spinal SFT/HPCs. Here, we describe CNS SFT/HPCs and predictors for recurrence, metastases, and death, in spinal and intracranial SFT/HPCs, separately. We collected data from studies with patient-level data available on primary SFT/HPCs from multiple online databases. Clinico-demographic data, surgical outcomes, recurrence, metastases, and death rates were abstracted. We used logistic and Cox regression models to identify predictors for recurrence, metastases, and death for spinal and intracranial SFT/HPCs. Twenty-nine studies (368 patients) were included. Higher histological grade and subtotal resection were associated with recurrence (p values < 0.05), while higher histological grade and recurrence (p values < 0.005) were associated with metastases formation. Time to recurrence (p < 0.005) and metastases (p < 0.001) formation were shorter for spinal SFT/HPCs. Death rates were higher among intracranial SFT/HPC patients (p value = 0.001). Among patients with higher histological grade, rates of metastases formation were different between intracranial and spinal SFT/HPCs. Risk of metastases was higher in the first 5 years from surgery for both intracranial and spinal SFT/HPCs. Meningeal SFT/HPCs patients have high rates of recurrence and metastasis, which occur mostly within the first 5 years after diagnosis. Spinal and intracranial SFT/HPCs show similar behavior, but spinal SFT/HPCs tend to develop metastases and recurrences in a shorter interval of time. Careful follow-up for spinal SFT/HPCs should be considered because spinal cases seem to be slightly more aggressive and require more attention.

Indexed as

Brain NeoplasmsHemangiopericytomaHumansMeningeal NeoplasmsNeoplasm MetastasisNeoplasm Recurrence, LocalPrognosisProspective StudiesRetrospective StudiesRisk FactorsSolitary Fibrous TumorsSpinal NeoplasmsSurvival RateHemangiopericytoma metastasisMeningeal hemangiopericytomaMeningeal solitary fibrous tumorSolitary fibrous tumor metastasisSpinal hemangiopericytomaSpinal solitary fibrous tumor

Identifiers

PMID32556679

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.