Evidence map›Paper›PMID 32556650›Full record

ArticleInternational journal of colorectal disease2020

Predictive value of the sentinel lymph node procedure in the staging of non-metastatic colorectal cancer.

A Carrara, M Motter, D Amabile, L Pellecchia, P Moscatelli, R Pertile, M Barbareschi, N L Decarli, M Ferrari, G Tirone

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Article in International journal of colorectal disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

A CarraraDepartment of General Surgery, S. Chiara Hospital, Trento, Italy. alessandro.carrara@apss.tn.it.ORCID http://orcid.org/0000-0002-9508-335X
M MotterDepartment of General Surgery, S. Chiara Hospital, Trento, Italy.
D AmabileDepartment of General Surgery, S. Chiara Hospital, Trento, Italy.
L PellecchiaDepartment of General Surgery, S. Chiara Hospital, Trento, Italy.
P MoscatelliDepartment of General Surgery, S. Chiara Hospital, Trento, Italy.
R PertileDepartment of Clinical and Evaluative Epidemiology, Health Service of Trento, Trento, Italy.
M BarbareschiDepartment of Anatomical Pathology, S. Chiara Hospital, Trento, Italy.
N L DecarliDepartment of Anatomical Pathology, S. Chiara Hospital, Trento, Italy.
M FerrariDepartment of Radiology, S. Chiara Hospital, Trento, Italy.
G TironeDepartment of General Surgery, S. Chiara Hospital, Trento, Italy.
Ospedale Santa Chiara · ITProvincia Autonoma di Trento · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDespite the recent growing interest of the scientific community, there is still no consensus on the actual applicability and effectiveness of sentinel lymph node (SL) procedure in colon cancers. This study aims to quantify feasibility, detection rate, negative predictive value, and accuracy of the SL identified with fluorescent dye in early colon cancers (ECC).

methodsThis study conducted a consecutive sampling of 95 patients with non-metastatic colorectal cancer who have been treated with laparoscopic colon resection and complete mesocolic excision after a 25-mg indocyanine green peritumoral laparoscopic injection and SL identification with a near-infrared camera. The SL was later isolated and sent to ultra-staging.

resultsNinety-five patients with an average age of 71 (range 37-90) and a mean BMI of 25 (range 18-39) have been recruited. On the patient sample (92 Pts), an average of 1.49 SL (range 1-5) and a mean time of 4 min were identified. The detection rate was 96.8% and the negative predictive value and accuracy rates were 96.2% and 93.4%, respectively.

conclusionsMapping the SL with fluorescent dye can play an important role in the treatment of colon cancers, particularly those at early stages, and can lead to ultra-conservative surgery.

Indexed as

Colonic NeoplasmsSentinel Lymph NodeAgedHumansIndocyanine GreenLymphatic MetastasisLymph Node ExcisionLymph NodesNeoplasm StagingSentinel Lymph Node BiopsyIndocyanine GreenAdjuvant chemotherapyColorectal cancerIndocyanine greenMicrometastasesSentinel lymph nodeUpstaging

Identifiers

PMID32556650
OpenAlexW3036332182

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.