Evidence map›Paper›PMID 32556576›Full record

ArticlePediatric radiology2020

Dual-source computed tomography of the lung with spectral shaping and advanced iterative reconstruction: potential for maximum radiation dose reduction.

Matthias Wetzl, Matthias S May, Daniel Weinmann, Matthias Hammon, Christoph Treutlein, Martin Zeilinger, Alexander Kiefer, Regina Trollmann, Joachim Woelfle, Michael Uder and 1 more

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Article in Pediatric radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Matthias WetzlDepartment of Radiology, University Hospital Erlangen, Erlangen, Germany. Matthias.wetzl@uk-erlangen.de.ORCID 0000-0001-9980-9528
Matthias S MayDepartment of Radiology, University Hospital Erlangen, Erlangen, Germany.
Daniel WeinmannDepartment of Radiology, University Hospital Erlangen, Erlangen, Germany.
Matthias HammonDepartment of Radiology, University Hospital Erlangen, Erlangen, Germany.
Christoph TreutleinDepartment of Radiology, University Hospital Erlangen, Erlangen, Germany.
Martin ZeilingerDepartment of Radiology, University Hospital Erlangen, Erlangen, Germany.
Alexander KieferDepartment of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Erlangen, Germany.
Regina TrollmannDepartment of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Erlangen, Germany.
Joachim WoelfleDepartment of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Erlangen, Germany.
Michael UderDepartment of Radiology, University Hospital Erlangen, Erlangen, Germany.
Oliver RompelDepartment of Radiology, University Hospital Erlangen, Erlangen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRadiation dose at CT should be as low as possible without compromising diagnostic quality.

objectiveTo assess the potential for maximum dose reduction of pediatric lung dual-source CT with spectral shaping and advanced iterative reconstruction (ADMIRE). MATERIALS AND

methodsWe retrospectively analyzed dual-source CT acquisitions in a full-dose group (FD: 100 kV, 64 reference mAs) and in three groups with spectral shaping and differing reference mAs values (Sn: 100 kV, 96/64/32 reference mAs), each group consisting of 16 patients (age mean 11.5 years, standard deviation 4.8 years, median 12.8 years, range 1.3-18 years). Advanced iterative reconstruction of images was performed with different strengths (FD: ADMIRE Level 2; Sn: ADMIRE Levels 2, 3 and 4). We analyzed dose parameters and measured noise. Diagnostic confidence and detectability of lung lesions as well as anatomical structures were assessed using a Likert scale (from 1 [unacceptable] to 4 [fully acceptable]).

resultsCompared to full dose, effective dose was reduced to 16.7% in the Sn 96 group, 11.1% in Sn64, and 5.5% in Sn32 (P<0.001). Noise values of Sn64

conclusionIn pediatric lung dual-source CT, spectral shaping together with ADMIRE 4 enable radiation dose reduction to about 10% of a full-dose protocol while maintaining an acceptable diagnostic quality.

Indexed as

Radiation DosageRadiographic Image Interpretation, Computer-AssistedAdolescentChildChild, PreschoolFemaleHumansInfantLung DiseasesMaleRetrospective StudiesTomography, X-Ray ComputedAdolescentsAdvanced iterative reconstructionChildrenDual-source computed tomographyLungRadiation dose reductionSpectral shapingTin prefiltration

Identifiers

PMID32556576
PMCPMC7398955

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.