Evidence map›Paper›PMID 32556559›Full record

ArticleWorld journal of urology2021

Comparison of renal functional outcomes of active surveillance and partial nephrectomy in the management of oncocytoma.

Margaret F Meagher, Brian R Lane, Umberto Capitanio, Reza Mehrazin, Aaron W Bradshaw, Sabrina Noyes, Alessandro Larcher, Ahmed Eldefrawy, Fady Ghali, Devin Patel and 7 more

Abstract readComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Margaret F MeagherDepartment of Urology, UC San Diego School of Medicine, 3855 Health Sciences Drive, 0987, La Jolla, CA, 92093-0987, USA.
Brian R LaneDepartment of Urology, Spectrum Health, Grand Rapids, MI, USA.
Umberto CapitanioDepartment of Urology, IRCCS Ospedale San Raffaele, Milan, Italy.
Reza MehrazinDepartment of Urology, Mt. Sinai School of Medicine, New York, NY, USA.
Aaron W BradshawDepartment of Urology, UC San Diego School of Medicine, 3855 Health Sciences Drive, 0987, La Jolla, CA, 92093-0987, USA.
Sabrina NoyesDepartment of Urology, Spectrum Health, Grand Rapids, MI, USA.
Alessandro LarcherDepartment of Urology, IRCCS Ospedale San Raffaele, Milan, Italy.
Ahmed EldefrawyDepartment of Urology, UC San Diego School of Medicine, 3855 Health Sciences Drive, 0987, La Jolla, CA, 92093-0987, USA.
Fady GhaliDepartment of Urology, UC San Diego School of Medicine, 3855 Health Sciences Drive, 0987, La Jolla, CA, 92093-0987, USA.
Devin PatelDepartment of Urology, UC San Diego School of Medicine, 3855 Health Sciences Drive, 0987, La Jolla, CA, 92093-0987, USA.
Jacob BruiniusDepartment of Urology, Spectrum Health, Grand Rapids, MI, USA.
Raksha DuttDepartment of Urology, UC San Diego School of Medicine, 3855 Health Sciences Drive, 0987, La Jolla, CA, 92093-0987, USA.
Cathrine KeinerDepartment of Urology, UC San Diego School of Medicine, 3855 Health Sciences Drive, 0987, La Jolla, CA, 92093-0987, USA.
Nathan MillerDepartment of Urology, UC San Diego School of Medicine, 3855 Health Sciences Drive, 0987, La Jolla, CA, 92093-0987, USA.
Fang WanDepartment of Urology, UC San Diego School of Medicine, 3855 Health Sciences Drive, 0987, La Jolla, CA, 92093-0987, USA.
Francesco MontorsiDepartment of Urology, IRCCS Ospedale San Raffaele, Milan, Italy.
Ithaar H DerweeshDepartment of Urology, UC San Diego School of Medicine, 3855 Health Sciences Drive, 0987, La Jolla, CA, 92093-0987, USA. iderweesh@gmail.com.ORCID http://orcid.org/0000-0002-8673-0711
University of California San Diego · USIRCCS Ospedale San Raffaele · ITSpectrum Health · USUC San Diego Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare functional outcomes of partial nephrectomy (PN) and active surveillance (AS) in oncocytoma.

methodsMulticenter retrospective analysis of patients with oncocytoma managed with PN or AS (biopsy-confirmed). Primary outcome development of de novo chronic kidney disease (CKD) (eGFR < 60 mL/min/1.73m

results295 patients were analyzed (224 PN/71 AS, median follow-up 37.4 months). No differences were noted for clinical tumor size (AS 2.6 vs. PN 2.9 cm, p = 0.108), and baseline eGFR (AS 79.6 vs. PN 77, p = 0.9670). Median change in tumor diameter for AS was 0.42 cm. Compared to PN, AS had deltaGFR (-15.3 vs. -6.4 mL/min/1.73m

conclusionAS was associated with greater functional decline than PN in oncocytoma. PN may be considered to optimalize renal functional preservation in select circumstances. Further investigation into mechanisms of functional decline in oncocytoma is requisite.

Indexed as

Watchful WaitingAdenoma, OxyphilicAgedFemaleHumansKidneyKidney NeoplasmsMaleMiddle AgedNephrectomyRetrospective StudiesTreatment OutcomeActive surveillanceChronic kidney diseaseGlomerular filtration rateKidney neoplasmOncocytomaPartial nephrectomy

Identifiers

PMID32556559
OpenAlexW3036118423

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.