Evidence map›Paper›PMID 32556429›Full record

ArticleEuropean biophysics journal : EBJ2020

Ligand-receptor-mediated attachment of lipid vesicles to a supported lipid bilayer.

Vladimir P Zhdanov

Open access · hybridAbstract read
In one paragraph

Article in European biophysics journal : EBJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 2 countries.

Vladimir P ZhdanovSection of Biological Physics, Department of Physics, Chalmers University of Technology, Göteborg, Sweden. zhdanov@chalmers.se.ORCID http://orcid.org/0000-0002-0167-8783
Boreskov Institute of Catalysis · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interaction of exosomes (cell-secreted [Formula: see text]100 nm-sized extracellular vesicles) or membrane-enveloped virions with cellular lipid membranes is often mediated by relatively weak ligand-receptor bonds. Interactions of this type can be studied using vesicles and observing their attachment to receptors located in a lipid bilayer formed at a solid surface. The contact region between a vesicle and the supported lipid bilayer and accordingly the number of ligand-receptor pairs there can be increased by deforming a vesicle. Herein, I (i) estimate theoretically the corresponding deformation energy assuming a disk-like or elongated shape of vesicles, (ii) present the equations allowing one to track such deformations by employing total internal reflection fluorescence microscopy and surface plasmon resonance, and (iii) briefly discuss some related experimental studies.

Indexed as

Models, MolecularExtracellular VesiclesLigandsLipid BilayersMicroscopy, FluorescenceThermodynamicsLigandsLipid BilayersMultivalent ligand-receptor interactionSupportVesicles

Identifiers

PMID32556429
PMCPMC7351846
OpenAlexW3035769530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.