Trial reportExperimental brain research2020
Multi-session anodal transcranial direct current stimulation enhances lower extremity functional performance in healthy older adults.
Trial report in Experimental brain research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- The effect of transcranial direct current stimulation on static and dynamic posture control in the elderly: a systematic review and meta-analysis.Frontiers in aging neuroscience · 2025Pooled it
- Transcranial direct current stimulation facilitates backward walking training.Experimental brain research · 2024Trial
- Effects of active and sham tDCS on the soleus H-reflex during standing.Experimental brain research · 2023Trial
- Targeted tDCS Mitigates Dual-Task Costs to Gait and Balance in Older Adults.Annals of neurology · 2021Trial
- Combining transcranial direct current stimulation with a motor-cognitive task: the impact on dual-task walking costs in older adults.Journal of neuroengineering and rehabilitation · 2021Trial
- Enhancing Balance and Walking Endurance in Older Adults: The Potential of Transcranial Direct Current Stimulation as an Adjunct to Balance Training, a Randomized, Sham-Controlled, Clinical Trial.Healthcare (Basel, Switzerland) · 2025Article
- Comparison of stimulation sites enhancing dual-task performance using transcranial direct current stimulation in Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Transcranial Direct Current Stimulation over the Temporoparietal Junction Modulates Posture Control in Unfamiliar Environments.Brain sciences · 2023Article
- Chronic Functional Adaptations Induced by the Application of Transcranial Direct Current Stimulation Combined with Exercise Programs: A Systematic Review of Randomized Controlled Trials.Journal of clinical medicine · 2023Review
- Faster Walking Speeds Require Greater Activity from the Primary Motor Cortex in Older Adults Compared to Younger Adults.Sensors (Basel, Switzerland) · 2023Article
- Is Anodal Transcranial Direct Current Stimulation an Effective Ergogenic Technology in Lower Extremity Sensorimotor Control for Healthy Population? A Narrative Review.Brain sciences · 2022Review
- Review of tDCS Configurations for Stimulation of the Lower-Limb Area of Motor Cortex and Cerebellum.Brain sciences · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to examine the effects of 5 days of anodal-transcranial direct current stimulation (a-tDCS) over the primary motor cortex (M1) on lower extremity functional performance in healthy elderly people. This was a randomized, double-blinded, sham-controlled study whereby 32 healthy older individuals participated in two groups. The intervention group received 20 min of a-tDCS (1 mA) over the M1 on five consecutive days. The sham group received the same stimulation, but the tDCS device was turned off after 30 s of stimulation. Participants were asked to perform the Timed Up and Go (TUG), 30-s Chair Stand Test (30-s CST), and a Modified Figure of Eight Walk Test (MFEWT) on the first day before tDCS application, immediately, 30 min, and 1 week after the last session of stimulation. Results of the a-tDCS group showed that most of the test values had significant changes in post-test assessments compared to the pre-test (p < 0.05). When comparing the anodal and sham tDCS groups, the results showed a significant improvement in TUG and time-MFEWT immediately after (p = 0.02, p = 0.01), 30 min after (p = 0.04, p = 0.01) and 1 week after the last session of stimulation (p = 0.01, p = 0.01). Improvements in performance of the 30-s CST and the number of steps-MFEWT were not significant, except at 1 week after the last session for the steps-MFEWT (p = 0.04). The application of 20 min a-tDCS over the M1 for 5 consecutive days improves lower extremity functional performance in the healthy older participants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.