ArticleChemical senses2020
Identifying Treatments for Taste and Smell Disorders: Gaps and Opportunities.
Article in Chemical senses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Taste and Smell Disorders in Cancer Treatment: Results from an Integrative Rapid Systematic Review.International journal of molecular sciences · 2023Pooled it
- Qualitative Olfactory Dysfunction and COVID-19: An Evidence-Based Review with Recommendations for the Clinician.American journal of rhinology & allergy · 2023Pooled it
- COVID-19 as a worldwide selective event and bitter taste receptor polymorphisms: An ecological correlational study.International journal of biological macromolecules · 2021Pooled it
- Validation of the Tamil Version of the Taste and Smell Questionnaire for Assessing Sensory Dysfunction in Head and Neck Cancer Patients Undergoing Chemoradiotherapy.Asian Pacific journal of cancer prevention : APJCP · 2026Article
- Long-term follow-up of autologous nasal epithelial stem cell transplantation for congenital olfactory disorders in children.World journal of stem cells · 2025Article
- Buccodental Toxicities Induced by Tyrosine Kinase Inhibitors in Patients Diagnosed with Renal Cell Carcinoma-A Literature Review.Dentistry journal · 2025Review
- Periodontitis is associated with impaired olfactory function: A clinical study.Journal of periodontal research · 2025Article
- Patients with Taste Disorders in a Hospital's Dental Department and Strategies for Taste Disorders.Biomedicines · 2024Article
- Noninvasive Diagnostic Method to Objectively Measure Olfaction and Diagnose Smell Disorders by a Molecularly Targeted Fluorescence Imaging Agent.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024Article
- Taste and Smell Alterations (TSAs) in Cancer Patients.Diseases (Basel, Switzerland) · 2024Review
- Article
- Integrating the patient's voice into the research agenda for treatment of chemosensory disorders.Chemical senses · 2024Article
- Photobiomodulation of Neurogenesis through the Enhancement of Stem Cell and Neural Progenitor Differentiation in the Central and Peripheral Nervous Systems.International journal of molecular sciences · 2023Review
- Text-based predictions of COVID-19 diagnosis from self-reported chemosensory descriptions.Communications medicine · 2023Article
- Interleukin (IL)-1 Receptor Signaling Is Required for Complete Taste Bud Regeneration and the Recovery of Neural Taste Responses following Axotomy.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Olfactory Function and Olfactory Disorders.Laryngo- rhino- otologie · 2023Article
- Characterization of human oxidoreductases involved in aldehyde odorant metabolism.Scientific reports · 2023Article
- Olfactory Dysfunction: Etiology, Diagnosis, and Treatment.Deutsches Arzteblatt international · 2023Review
- Chemosensory Ability and Sensitivity in Health and Disease: Epigenetic Regulation and COVID-19.International journal of molecular sciences · 2023Review
- Establishing UK research priorities in smell and taste disorders: A James Lind alliance priority setting partnership.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 12 institutions in 2 countries.
Funding
Abstract
The chemical senses of taste and smell play a vital role in conveying information about ourselves and our environment. Tastes and smells can warn against danger and also contribute to the daily enjoyment of food, friends and family, and our surroundings. Over 12% of the US population is estimated to experience taste and smell (chemosensory) dysfunction. Yet, despite this high prevalence, long-term, effective treatments for these disorders have been largely elusive. Clinical successes in other sensory systems, including hearing and vision, have led to new hope for developments in the treatment of chemosensory disorders. To accelerate cures, we convened the "Identifying Treatments for Taste and Smell Disorders" conference, bringing together basic and translational sensory scientists, health care professionals, and patients to identify gaps in our current understanding of chemosensory dysfunction and next steps in a broad-based research strategy. Their suggestions for high-yield next steps were focused in 3 areas: increasing awareness and research capacity (e.g., patient advocacy), developing and enhancing clinical measures of taste and smell, and supporting new avenues of research into cellular and therapeutic approaches (e.g., developing human chemosensory cell lines, stem cells, and gene therapy approaches). These long-term strategies led to specific suggestions for immediate research priorities that focus on expanding our understanding of specific responses of chemosensory cells and developing valuable assays to identify and document cell development, regeneration, and function. Addressing these high-priority areas should accelerate the development of novel and effective treatments for taste and smell disorders.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.