Evidence map›Paper›PMID 32555703›Full record

ArticlePloS one2020

HIV testing, care and viral suppression among men who have sex with men and transgender individuals in Johannesburg, South Africa.

Elizabeth Fearon, Siyanda Tenza, Cecilia Mokoena, Kerushini Moodley, Adrian D Smith, Adam Bourne, Peter Weatherburn, Thesla Palanee-Phillips

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
0.4field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Elizabeth FearonDepartment of Global Health and Development, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Siyanda TenzaWits Reproductive Health and HIV Institute, Johannesburg, South Africa.
Cecilia MokoenaWits Reproductive Health and HIV Institute, Johannesburg, South Africa.
Kerushini MoodleyWits Reproductive Health and HIV Institute, Johannesburg, South Africa.
Adrian D SmithNuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.ORCID 0000-0003-0036-1490
Adam BourneAustralian Research Centre in Sex, Health and Society, LaTrobe University, Melbourne, Australia.
Peter WeatherburnDepartment of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Thesla Palanee-PhillipsWits Reproductive Health and HIV Institute, Johannesburg, South Africa.
Perinatal HIV Research Unit · ZALa Trobe University · AULondon School of Hygiene & Tropical Medicine · GBRoyal Society of Tropical Medicine and Hygiene · GBUniversity of Oxford · GB

Funding

Medical Research Council MR/S020462/1
6 · The paper itself

Abstract

introductionMen who have sex with men and transgender individuals (MSM/TG) carry a disproportionately high burden of HIV, including in South Africa. However, there are few empirical population-representative estimates of viral suppression and the HIV care cascade including HIV testing among this population, nor of factors associated with these outcomes.

methodsWe conducted a respondent driven sampling (RDS) survey among 301 MSM/TG in Johannesburg in 2017. Participants gave blood samples for HIV testing and viral load. Participants self-completed a survey including sociodemographics, HIV testing history, and engagement in care. We calculated RDS-II weighted estimates of the percentage of HIV-negative MSM/TG reporting HIV testing in the previous 6 months, their testing experience and preferences. Among those HIV-positive, we estimated the percentage status-aware, on ART, and virally suppressed (<50 viral copies/ml plasma). We conducted RDS-weighted robust Poisson regression to obtain weighted prevalence ratios of factors associated with 1) HIV testing among those HIV-negative; and 2) viral suppression among those HIV-positive.

resultsThere were 118/300 HIV-positive MSM/TG, (37.5%). Of the HIV-negative MSM/TG, 61.5% reported that they had tested for HIV in the previous 6 months, which was associated with selling sex to men (Prevalence Ratio = 1.67, 95% CI 1.36-2.05). There were 76/118 HIV-positive MSM/TG (56.5%) who reported having previously tested positive for HIV and 39/118 (30.0%) who reported current ART. There were 58/118 HIV-positive MSM/TG with viral loads <50 copies/ml plasma (46.9%). Viral suppression was associated with older age (adjusted PR = 1.03, 95% CI 1.00-1.06 for each year), neighbourhood, and having bought sex from men (adjusted PR = 1.53, 95% CI 1.12-2.08).

conclusionsHIV prevalence was very high. Viral suppression among those HIV-positive was similar to the general male population in South Africa, but remains far short of national and international targets. A majority of HIV-negative MSM/TG had HIV tested in the previous 6 months, though there is room for improvement.

Indexed as

Homosexuality, MaleTransgender PersonsAdolescentAdultAIDS SerodiagnosisAntiretroviral Therapy, Highly ActiveFemaleHealth BehaviorHIV InfectionsHumansMalePrevalenceSocioeconomic FactorsSouth AfricaSurveys and QuestionnairesViral Load

Identifiers

PMID32555703
PMCPMC7299351
OpenAlexW3036214762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.