ArticlePLoS genetics2020
Behavioral and brain- transcriptomic synchronization between the two opponents of a fighting pair of the fish Betta splendens.
Article in PLoS genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Differences in Colour Pattern, Behaviour and Gene Expression in the Brain Suggest Divergent Camouflage Strategies in Sympatric Reef Fish Species.Molecular ecology · 2025Article
- Novel behavioural assays reveal sex-specific behavioural syndromes in anemonefish.Journal of fish biology · 2025Article
- Coordination and persistence of aggressive visual communication in Siamese fighting fish.Cell reports · 2025Article
- Single nucleus RNA-sequencing reveals transcriptional synchrony across different relationships.bioRxiv : the preprint server for biology · 2024Article
- Neural mechanisms of mutualistic fish cleaning behaviour: a study in the wild.Biology letters · 2024Article
- Article
- Transcriptomic responses to location learning by honeybee dancers are partly mirrored in the brains of dance-followers.Proceedings. Biological sciences · 2023Article
- Sexual coordination in a whole-brain map of prairie vole pair bonding.bioRxiv : the preprint server for biology · 2023Article
- Behavioral and endocrine responses to noninteractive live and video conspecifics in males of the Siamese fighting fish.Current zoology · 2023Article
- Care and Use of Siamese Fighting Fish (Comparative medicine · 2022Article
- Alternative splicing plays key roles in response to stress across different stages of fighting in the fish Betta splendens.BMC genomics · 2022Article
- Data of RNA-seq transcriptomes in the brain associated with aggression in males of the fishData in brief · 2021Article
- Dynamic neurogenomic responses to social interactions and dominance outcomes in female paper wasps.PLoS genetics · 2021Article
- Physiology, endocrinology and chemical communication in aggressive behaviour of fishes.Journal of fish biology · 2021Review
- Overview of the betta fish genome regarding species radiation, parental care, behavioral aggression, and pigmentation model relevant to humans.Genes & genomics · 2021Review
- Motor Stereotypic Behavior Was Associated With Immune Response in Macaques: Insight From Transcriptome and Gut Microbiota Analysis.Frontiers in microbiology · 2021Article
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22 authors.
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Abstract
Conspecific male animals fight for resources such as food and mating opportunities but typically stop fighting after assessing their relative fighting abilities to avoid serious injuries. Physiologically, how the fighting behavior is controlled remains unknown. Using the fighting fish Betta splendens, we studied behavioral and brain-transcriptomic changes during the fight between the two opponents. At the behavioral level, surface-breathing, and biting/striking occurred only during intervals between mouth-locking. Eventually, the behaviors of the two opponents became synchronized, with each pair showing a unique behavioral pattern. At the physiological level, we examined the expression patterns of 23,306 brain transcripts using RNA-sequencing data from brains of fighting pairs after a 20-min (D20) and a 60-min (D60) fight. The two opponents in each D60 fighting pair showed a strong gene expression correlation, whereas those in D20 fighting pairs showed a weak correlation. Moreover, each fighting pair in the D60 group showed pair-specific gene expression patterns in a grade of membership analysis (GoM) and were grouped as a pair in the heatmap clustering. The observed pair-specific individualization in brain-transcriptomic synchronization (PIBS) suggested that this synchronization provides a physiological basis for the behavioral synchronization. An analysis using the synchronized genes in fighting pairs of the D60 group found genes enriched for ion transport, synaptic function, and learning and memory. Brain-transcriptomic synchronization could be a general phenomenon and may provide a new cornerstone with which to investigate coordinating and sustaining social interactions between two interacting partners of vertebrates.
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