Evidence map›Paper›PMID 32555553›Full record

SynthesisOncology nursing forum2020

Comparing Interventions for Management of Hot Flashes in Patients With Breast and Prostate Cancer: A Systematic Review With Meta-Analyses.

Brian Hutton, Mona Hersi, Wei Cheng, Misty Pratt, Pauline Barbeau, Sasha Mazzarello, Nadera Ahmadzai, Becky Skidmore, Scott C Morgan, Louise Bordeleau and 5 more

2 registry-linked trialsOpen access · greenAbstract readComparative StudySystematic ReviewNetwork Meta-Analysis
In one paragraph

Synthesis in Oncology nursing forum, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05222464 phase4completednot on this mapstarted 2022, after this paper: background citation

Utilizing MyChart to Assess the Effectiveness of Interventions for Vasomotor Symptoms: A Feasibility Study (REaCT-Hot Flashes Pilot)

TypeinterventionalSponsorOttawa Hospital Research InstituteRan2022 to 2022Enrolled56ConditionsBreast CancerArmsStandard of care treatments
NCT07422727 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

COOLVAS: Exploring the Feasibility and Impact of Cooling Mats on Vasomotor Symptoms in Patients Receiving Endocrine Treatment: A Pilot Study

TypeinterventionalSponsorSligo General HospitalRan2025 to 2026Enrolled40ConditionsHot Flashes, Sleep, Hormonal, CancerArmsCooling Gel Mats
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Using machine learning to predict individual patient toxicities from cancer treatments.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  6. Vasomotor symptoms in early breast cancer-a "real world" exploration of the patient experience.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Brian HuttonUniversity of Ottawa.ORCID 0000-0001-5662-8647
Mona HersiOttawa Hospital Research Institute.ORCID 0000-0003-1784-1167
Wei ChengOttawa Hospital Research Institute.
Misty PrattOttawa Hospital Research Institute.ORCID 0000-0001-9247-9036
Pauline BarbeauOttawa Hospital Research Institute.
Sasha MazzarelloOttawa Hospital Research Institute.ORCID 0000-0003-1299-5132
Nadera AhmadzaiOttawa Hospital Research Institute.ORCID 0000-0002-8180-1568
Becky SkidmoreOttawa Hospital Research Institute.ORCID 0000-0001-8293-9238
Scott C MorganUniversity of Ottawa.
Louise BordeleauMcMaster University.
Pamela K GinexOncology Nursing Society.ORCID 0000-0003-3878-4835
Behnam SadeghiradMcMaster University.ORCID 0000-0001-9422-5232
Rebecca L MorganMcMaster University.
Katherine Marie ColeUniversity of Ottawa.
Mark ClemonsUniversity of Ottawa.ORCID 0000-0002-0738-2713
Ottawa Hospital Research InstituteUniversity of Ottawa · CAMcMaster University · CAOttawa Hospital · CAOncology Nursing Society · US

Funding

Cochrane Complementary Medicine Field: Resource for ResearchR24AT001293 · NCCIH · UNIVERSITY OF MARYLAND BALTIMORE · PI BERMAN, BRIAN M, WIELAND, LISA SUSAN · 2003 to 2022
$9.4M
CIHRNCCIH NIH HHS R24 AT001293
6 · The paper itself

Abstract

problem identificationHot flashes are common and bothersome in patients with breast and prostate cancer and can adversely affect patients' quality of life. LITERATURE SEARCH: Databases were searched for randomized controlled trials (RCTs) evaluating the effects of one or more interventions for hot flashes in patients with a history of breast or prostate cancer. DATA EVALUATION: Outcomes of interest included changes in hot flash severity, hot flash frequency, quality of life, and harms. Pairwise meta-analyses and network meta-analyses were performed where feasible, with narrative synthesis used where required. SYNTHESIS: 40 RCTs were included. Findings from network meta-analysis for hot flash frequency suggested that several therapies may offer benefits compared to no treatment, but little data suggested differences between active therapies. Findings from network meta-analysis for hot flash score were similar. IMPLICATIONS FOR RESEARCH: Although many interventions may offer improvements for hot flashes versus no treatment, minimal data suggest important differences between therapies. SUPPLEMENTARY MATERIALS CAN BE FOUND BY VISITING HTTPS: //bit.ly/2WGzi30.

Indexed as

AdultAgedAged, 80 and overBreast NeoplasmsFemaleHot FlashesHumansMaleMenopauseMiddle AgedProstatic NeoplasmsQuality of Lifebreast cancerhot flashesmeta-analysisprostate cancersystematic review

Identifiers

PMID32555553
PMCPMC7891229
OpenAlexW3025963892

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.