Evidence map›Paper›PMID 32555468›Full record

ArticleScientific reports2020

Genetic variants associated with alcohol dependence co-ordinate regulation of ADH genes in gastrointestinal and adipose tissues.

Rebecca Hibberd, Evgeniia Golovina, Sophie Farrow, Justin M O'Sullivan

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Rebecca Hibberd *Liggins Institute, The University of Auckland, Auckland, New Zealand.
Evgeniia Golovina *Liggins Institute, The University of Auckland, Auckland, New Zealand.
Sophie FarrowLiggins Institute, The University of Auckland, Auckland, New Zealand.
Justin M O'SullivanLiggins Institute, The University of Auckland, Auckland, New Zealand. justin.osullivan@auckland.ac.nz.
University of Auckland · NZUniversity of Southampton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GWAS studies have identified genetic variants associated with Alcohol Dependence (AD), but how they link to genes, their regulation and disease traits, remains largely unexplored. Here we integrated information on the 3D genome organization with expression quantitative loci (eQTLs) analysis, using CoDeS3D, to identify the functional impacts of single nucleotide polymorphisms associated with AD (p < 1 × 10

Indexed as

Polymorphism, Single NucleotideAdipose TissueAlcohol DehydrogenaseAlcoholismGastrointestinal TractGenome-Wide Association StudyGenotypeHumansLinkage DisequilibriumLungQuantitative Trait LociAlcohol Dehydrogenase

Identifiers

PMID32555468
PMCPMC7303195
OpenAlexW3036600169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.