ArticleNature2020
Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping.
Open access · greenAbstract readComparative Study
In one paragraph
Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 223 papers.
0numbers the graph read from it
0cells of the map it votes in
223citing papers in PubMed
15.4field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
223 citing papers in PubMed, 320 citations in OpenAlex.
- RNA N4-acetylcytidine modification in health and cancer: molecular mechanisms, cellular plasticity, and therapeutic opportunities.Biomarker research · 2026Review
- Structural basis of nucleotide-dependent conformational switching of a CBS-family protein on the archaeal 50S ribosome.Science China. Life sciences · 2026Article
- NAT10 governs development through the Xrp1-mediated stress response rather than its RNA acetylation activity.Science advances · 2026Article
- Updated guide to RNA quantification by RNA sequencing and reverse transcription-qPCR.Molecules and cells · 2026Article
- N-Acetyltransferase 10 (NAT10) at the crossroads of metabolism, immunology, and cancer biology.Cancer metastasis reviews · 2026Review
- The pseudouridine synthase PUSL1 modifies U39 of mitochondrial tRNAs and is linked to human neurological phenotypes.Nucleic acids research · 2026Article
- Targeting NAT10 Activates Tumor-Intrinsic Immunity and Suppresses Tumor Progression in Head and Neck Squamous Cell Carcinoma.bioRxiv : the preprint server for biology · 2026Article
- The RNA helicase domain of NAT10 promotes the biogenesis of hypomodified ribosomes to enhance cancer cell proliferation.Nature communications · 2026Article
- Intermediate stages in the origin of metabolism at a phosphorylating hydrothermal vent.Science advances · 2026Article
- Evolution of the ribosomal exit tunnel through the eyes of the nascent chain.Nucleic acids research · 2026Article
- Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R-Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Structure of the NAT10 acetyltransferase and mechanism of tRNA acetylation.Nature communications · 2026Article
- OTTR-seq profiling reveals dynamic tRNA modification landscapes across diverse archaeal species.Genome biology · 2026Article
- The NAT10/c-Myc positive feedback loop orchestrates tRNA acCellular & molecular biology letters · 2026Article
- NAT10 inhibition alleviates renal tubular epithelial cell senescence by impeding ac4C acetylation of PAPP-A mRNA in diabetic nephropathy.Cell death & disease · 2026Article
- Programmable RNA acetylation with CRISPR-Cas13.Nature chemical biology · 2026Article
- Targeted RNA acetylation via a dCas13-guided engineered acetyl-transferase.Nature chemical biology · 2026Article
- Nanopore direct RNA sequencing and the epitranscriptome: Advances in mapping native RNA landscapes.iMeta · 2026Review
- Integrative interpretable learning reveals shared patterns of epitranscriptomic regulation across multiple cancer types.BMC biology · 2026Article
- NAT10/acProceedings of the National Academy of Sciences of the United States of America · 2026Article
163 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors at 8 institutions in 3 countries.
Aldema Sas-Chen *Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Justin M Thomas *National Cancer Institute, National Institutes of Health, Frederick, MD, USA.
Donna Matzov *Department of Structural Biology, Weizmann Institute of Science, Rehovot, Israel.
Masato TaokaDepartment of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Tokyo, Japan.
Kellie D NanceNational Cancer Institute, National Institutes of Health, Frederick, MD, USA.ORCID http://orcid.org/0000-0002-4396-9124
Ronit NirDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Keri M BrysonNational Cancer Institute, National Institutes of Health, Frederick, MD, USA.
Ran ShacharDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Geraldy L S LimanDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.
Brett W BurkhartDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.
Supuni Thalalla GamageNational Cancer Institute, National Institutes of Health, Frederick, MD, USA.ORCID http://orcid.org/0000-0002-1045-6306
Yuko NobeDepartment of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Tokyo, Japan.
Chloe A BrineyNational Cancer Institute, National Institutes of Health, Frederick, MD, USA.
Michaella J LevyStowers Institute for Medical Research, Kansas City, MO, USA.
Ryan T FuchsRNA Research Division, New England Biolabs, Inc, Ipswich, MA, USA.
G Brett RobbRNA Research Division, New England Biolabs, Inc, Ipswich, MA, USA.ORCID http://orcid.org/0000-0002-2382-2256
Jesse HartmannDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Sunny SharmaDepartment of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ, USA.ORCID http://orcid.org/0000-0001-8896-9016
Qishan LinRNA Epitranscriptomics and Proteomics Resource, University at Albany, Albany, NY, USA.ORCID http://orcid.org/0000-0002-1756-1432
Laurence FlorensStowers Institute for Medical Research, Kansas City, MO, USA.
Michael P WashburnStowers Institute for Medical Research, Kansas City, MO, USA.ORCID http://orcid.org/0000-0001-7568-2585
Toshiaki IsobeDepartment of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Tokyo, Japan.
Thomas J SantangeloDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA.
Moran Shalev-BenamiDepartment of Structural Biology, Weizmann Institute of Science, Rehovot, Israel. moransb@weizmann.ac.il.
Jordan L MeierNational Cancer Institute, National Institutes of Health, Frederick, MD, USA. jordan.meier@nih.gov.
Schraga SchwartzDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel. schwartz@weizmann.ac.il.ORCID http://orcid.org/0000-0002-3671-9709
Weizmann Institute of Science · ILNational Institutes of Health · USColorado State University · USStowers Institute for Medical Research · USTokyo Metropolitan University · JPNew England Biolabs (United States) · USRutgers, The State University of New Jersey · USUniversity at Albany, State University of New York · US
Funding
Targeting Cancer Through Modifications and MetabolismZIABC011488 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI MEIER, JORDAN L · 2013 to 2025
$21.3MMechanisms of Archaeal Transcription Termination - Administrative SupplementR01GM100329 · NIGMS · OHIO STATE UNIVERSITY · PI SANTANGELO, THOMAS JAMES · 2012 to 2021
$2.5MRegulation of Archaeal TranscriptionR35GM143963 · NIGMS · COLORADO STATE UNIVERSITY · PI Thomas James Santangelo · 2022 to 2026
$1.8MInhibitor Reprogramming of a Human Histone Deacetylase Protein Interaction NetworkR01GM112639 · NIGMS · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI FLORENS, LAURENCE ALEXANDRA · 2016 to 2020
$1.6MEuropean Research CouncilIntramural NIH HHS ZIA BC011488NIGMS NIH HHS R01 GM100329NIGMS NIH HHS R01 GM112639NIGMS NIH HHS R35 GM143963
Abstract
N
Indexed as
AcetylationEvolution, MolecularArchaeaConserved SequenceCryoelectron MicroscopyCytidineEukaryotic CellsHeLa CellsHumansModels, MolecularN-Terminal AcetyltransferasesRibosomesRNARNA, ArchaealRNA-Binding ProteinsSaccharomyces cerevisiaeCytidineN-acetylcytidineNAT10 protein, humanN-Terminal AcetyltransferasesRNARNA, ArchaealRNA-Binding ProteinsTHUMPD1 protein, human
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.