Observational studyHypertension research : official journal of the Japanese Society of Hypertension2020
Central blood pressure predicts the development of hypertension in the general population.
Observational study in Hypertension research : official journal of the Japanese Society of Hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.
- Effects of High-Intensity Interval Training on Central Blood Pressure: A Systematic Review and Meta-Analysis.Arquivos brasileiros de cardiologia · 2023Pooled it
- Association Between Arterial Stiffness and Blood Pressure Progression With Incident Hypertension: A Systematic Review and Meta-Analysis.Frontiers in cardiovascular medicine · 2022Pooled it
- Association of aortic root diameter and vascular function with an exaggerated blood pressure response to exercise among elite athletes.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Postmeal walking reduces nighttime central SBP and increases nocturnal dipping of SBP in healthy, physically inactive young women.Journal of hypertension · 2025Article
- Association Between Changes in Central Blood Pressure and Peripheral Blood Pressure With New-Onset Hypertension in a Chinese Community-Based Population.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Association of central blood pressure with an exaggerated blood pressure response to exercise among elite athletes.European journal of applied physiology · 2024Article
- Vascular function: a key player in hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Review
- Brazilian Guidelines of Hypertension - 2020.Arquivos brasileiros de cardiologia · 2021Article
- Comparison of Prevalent Hypertension by Aortic versus Brachial Blood Pressure Criteria for - A Pulse Wave Analysis Based Study from Adults of a City of West India.Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although elevated blood pressure results in arterial stiffening, the converse could also be true. Previous studies have suggested that increased arterial stiffness precedes the development of hypertension. Since central blood pressure is augmented following arterial stiffening, the predictive value of central blood pressure for detecting new-onset hypertension was investigated in the general population. A total of 7840 normotensive subjects (male, 4592; mean age, 51 years) were followed up for a median of 4 years, with the endpoint being the development of hypertension. During the actual follow-up period of 31636 person-years, hypertension developed in 2608 subjects. Kaplan-Meier analysis revealed an increase in the risk of hypertension across the quartiles of baseline central blood pressure (log-rank P < 0.001), with incidence rates of hypertension in the first, second, third, and fourth quartiles of 8.8%, 22.3%, 39.9%, and 63.2%, respectively. Multivariate Cox hazard analysis demonstrated an increased hazard ratio of incident hypertension across the quartiles after adjustment for possible factors. Repeating the multivariate Cox hazard analysis with central blood pressure as a continuous variable also identified central blood pressure at baseline as a significant predictor of new-onset hypertension (P < 0.001). These results suggest that central blood pressure is a significant predictor of new-onset hypertension in individuals without hypertension.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.