ArticleScientific reports2020
A validated computational framework to predict outcomes in TAVI.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Strain-Based Assessment of Post-TAVR Left Bundle Branch Block in Bicuspid Aortic Valve Using Patient-Specific Computational Modeling.Annals of biomedical engineering · 2026Article
- MVRepairAI: A machine learning-based system to predict surgical methods in mitral valve repair.JTCVS open · 2026Article
- Nationwide trends and in-hospital outcomes of surgical versus transcatheter aortic valve replacement in Japan: a real-world analysis using administrative data.Heart and vessels · 2026Article
- Computational modelling for personalized transcatheter aortic valve replacement planning: a systematic review of complications and decision support.Frontiers in digital health · 2026Review
- Credibility assessment of patient-specific modeling in transcatheter aortic valve implantation. I. A population-based validation of patient-specific modeling.APL bioengineering · 2025Article
- Credibility assessment of patient-specific modeling in transcatheter aortic valve implantation-Part 2: Uncertainty quantification and sensitivity analysis.APL bioengineering · 2025Article
- Predicting procedural outcomes in transcatheter aortic valve implantation: a scoping review of numerical patient-specific simulations.Progress in biomedical engineering (Bristol, England) · 2025Article
- Simulation for Procedural Planning and Intracardiac Echo for Enhancing Precision in Cardiac Interventions With a Focus on Left Atrial Appendage Closure.Structural heart : the journal of the Heart Team · 2025Review
- Morphology and calcification characterization in patients undergoing TAVI: A 3D statistical shape modelling study.PLOS digital health · 2025Article
- Simulation for Procedural Planning and Intracardiac Echo for Enhancing Precision in Cardiac Interventions With a Focus on Left Atrial Appendage Closure.Structural heart : the journal of the Heart Team · 2025Review
- Assessing post-TAVR cardiac conduction abnormalities risk using an electromechanically coupled beating heart.Biomechanics and modeling in mechanobiology · 2025Article
- AI-Powered Multimodal Modeling of Personalized Hemodynamics in Aortic Stenosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Fluid-Solid Interaction Analysis for Developing In-Situ Strain and Flow Sensors for Prosthetic Valve Monitoring.Sensors (Basel, Switzerland) · 2024Article
- The Application of Precision Medicine in Structural Heart Diseases: A Step towards the Future.Journal of personalized medicine · 2024Review
- On the Material Constitutive Behavior of the Aortic Root in Patients with Transcatheter Aortic Valve Implantation.Cardiovascular engineering and technology · 2024Article
- The role of computational methods in cardiovascular medicine: a narrative review.Translational pediatrics · 2024Review
- Parametric analysis of transcatheter aortic valve replacement in transcatheter aortic valve replacement: evaluation of coronary flow obstruction.Frontiers in bioengineering and biotechnology · 2023Article
- Calibration of Cohorts of Virtual Patient Heart Models Using Bayesian History Matching.Annals of biomedical engineering · 2023Article
- Validating In Silico and In Vitro Patient-Specific Structural and Flow Models with Transcatheter Bicuspid Aortic Valve Replacement Procedure.Cardiovascular engineering and technology · 2022Article
- Assessment of Paravalvular Leak Severity and Thrombogenic Potential in Transcatheter Bicuspid Aortic Valve Replacements Using Patient-Specific Computational Modeling.Journal of cardiovascular translational research · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Transcatheter aortic valve implantation (TAVI) still presents complications: paravalvular leakage (PVL) and onset of conduction abnormalities leading to permanent pacemaker implantation. Our aim was testing a validated patient-specific computational framework for prediction of TAVI outcomes and possible complications. Twenty-eight TAVI patients (14 SapienXT and 14 CoreValve) were retrospectively selected. Pre-procedural CT images were post-processed to create 3D patient-specific implantation sites. The procedures were simulated with finite element analysis. Simulations' results were compared against post-procedural clinical fluoroscopy and echocardiography images. The computational model was in good agreement with clinical findings: the overall stent diameter difference was 2.6% and PVL was correctly identified with a post-processing algorithm in 83% of cases. Strains in the implantation site were studied to assess the risk of conduction system disturbance and were found highest in the patient who required pacemaker implantation. This study suggests that computational tool could support safe planning and broadening of TAVI.
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