ArticleNature communications2020
Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis.
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In one paragraph
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 141 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
141citing papers in PubMed, 2 pooled it
12.2field-weighted citation impact, top 1% of its field
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Who cites it
141 citing papers in PubMed, 2 syntheses or guidelines pooled it, 191 citations in OpenAlex.
- Deep learning and genome-wide association meta-analyses of bone marrow adiposity in the UK Biobank.Nature communications · 2025Pooled it
- Guidelines for Biobanking of Bone Marrow Adipose Tissue and Related Cell Types: Report of the Biobanking Working Group of the International Bone Marrow Adiposity Society.Frontiers in endocrinology · 2021Guideline
- Effect of artificial gravity on calcaneal bone marrow adipose tissue and mineral content in female and male participants in 60 days of bed rest.Experimental physiology · 2026Trial
- Innate [European journal of nuclear medicine and molecular imaging · 2025Trial
- Loading Enhances Glucose Uptake in Muscles, Bones, and Bone Marrow of Lower Extremities in Humans.The Journal of clinical endocrinology and metabolism · 2024Trial
- Regional variation in vertebral bone marrow adiposity: a population-based atlas of age- and sex-specific patterns.Skeletal radiology · 2026Article
- Not just fillers: the emerging role of bone marrow adipocytes in bone and bone marrow homeostasis.Biology open · 2026Review
- Potential Role for the Ubiquitin Ligase SIAH2 in Modulating Bone Morphology and Adiposity.Calcified tissue international · 2026Article
- Transcriptomic analysis of bone marrow adipose tissue reveals enrichment in lipid transport in response to a Western diet.Endocrinology · 2026Article
- Exercise and Fat: A Primer.Sports medicine - open · 2026Review
- Association of habitual diet and bone marrow adipose tissue - magnetic resonance imaging in a population-based sample.Nutrition journal · 2026Article
- Article
- Role of adipose tissue in cardiovascular health and diseases.Chinese medical journal · 2026Review
- Article
- Adiponectin exerts sex-dependent effects on lipid, amino acid, and glucose metabolism during caloric restriction.PLoS biology · 2026Article
- Preserved Mandibular Bone Microarchitecture Following Ovariectomy-induced Osteoporosis is Associated with a Specific Fatty Acid Composition in the Rat.Calcified tissue international · 2026Article
- Caloric restriction exerts site-, sex-, and duration-dependent effects on skeletal structure and bone marrow adiposity.The Journal of endocrinology · 2026Article
- First human whole-body biodistribution and dosimetry analysis of [European journal of nuclear medicine and molecular imaging · 2026Article
- Doxorubicin enhances adipogenesis in an FGF2-dependent manner and induces a tumour-promoting secretory phenotype.Journal of bone oncology · 2026Article
- Fostering the next generation of bone marrow adiposity researchers: the 3rd International Bone Marrow Adiposity Society Summer School 2025 report.Biology open · 2026Article
81 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
28 authors at 6 institutions in 3 countries.
Karla J SuchackiUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.ORCID http://orcid.org/0000-0002-4688-4126
Adriana A S TavaresUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.
Domenico MattiucciUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.
Erica L SchellerDivision of Bone and Mineral Diseases, Department of Medicine, Washington University, St. Louis, MO, USA.ORCID http://orcid.org/0000-0002-1551-3816
Giorgos PapanastasiouEdinburgh Imaging, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0002-1939-296X
Calum GrayEdinburgh Imaging, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0002-2816-4707
Matthew C SintonUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.ORCID http://orcid.org/0000-0003-1292-799X
Lynne E RamageUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.
Wendy A McDougaldUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.
Andrea LovdelUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.ORCID http://orcid.org/0000-0002-4262-8491
Richard J SulstonUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.
Benjamin J ThomasUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.ORCID http://orcid.org/0000-0001-8344-5256
Bonnie M NicholsonUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.
Amanda J DrakeUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.ORCID http://orcid.org/0000-0001-8633-333X
Carlos J Alcaide-CorralUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.ORCID http://orcid.org/0000-0002-3002-0649
Diana SaidUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.
Antonella PoloniDipartimento di Scienze Cliniche e Molecolari, Clinica di Ematologia, Università Politecnica delle Marche, Ancona, Italy.ORCID http://orcid.org/0000-0002-4221-4125
Saverio CintiDipartimento di Scienze Cliniche e Molecolari, Clinica di Ematologia, Università Politecnica delle Marche, Ancona, Italy.ORCID http://orcid.org/0000-0003-0362-5017
Gavin J MacphersonDepartment of Orthopaedic Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK.
Marc R DweckUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.
Jack P M AndrewsUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.ORCID http://orcid.org/0000-0003-4593-9655
Michelle C WilliamsUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.ORCID http://orcid.org/0000-0003-3556-2428
Robert J WallaceDepartment of Orthopaedics, The University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0002-5740-460X
Edwin J R van BeekEdinburgh Imaging, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0002-2777-5071
Ormond A MacDougaldDepartment of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
Nicholas M MortonUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.ORCID http://orcid.org/0000-0001-8218-8462
Roland H StimsonUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.ORCID http://orcid.org/0000-0002-9002-6188
William P CawthornUniversity/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK. W.Cawthorn@ed.ac.uk.ORCID http://orcid.org/0000-0001-7832-5057
The Queen's Medical Research Institute · GBUniversity of Edinburgh · GBMarche Polytechnic University · ITEdinburgh Royal Infirmary · GBUniversity of Michigan · USWashington University in St. Louis · US
Funding
Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Scott Soleimanpour · 2013 to 2026
$24.3MPilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Joyce Lee · 2010 to 2026
$20.3MInterdisciplinary Study of Marrow Adiposity, Mineral Metabolism & Energy BalanceR24DK092759 · NIDDK · MAINEHEALTH · PI HOROWITZ, MARK C, MACDOUGALD, ORMOND A · 2011 to 2019
$13.0MNeural regulation of skeletal biology and periodontal disease progression in typeK99DE024178 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCHELLER, ERICA LYNN · 2014 to 2015
$203kBritish Heart Foundation FS/14/78/31020British Heart Foundation FS/17/51/33096British Heart Foundation RE/13/3/30183British Heart Foundation RG/16/10/32375Chief Scientist Office PCL/17/04Chief Scientist Office SCAF/17/02Medical Research Council MR/K010271/1Medical Research Council MR/M021394/1NIDCR NIH HHS K99 DE024178NIDDK NIH HHS N02 DK062876NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK089503NIDDK NIH HHS R24 DK092759Wellcome Trust
Abstract
Bone marrow adipose tissue (BMAT) comprises >10% of total adipose mass, yet unlike white or brown adipose tissues (WAT or BAT) its metabolic functions remain unclear. Herein, we address this critical gap in knowledge. Our transcriptomic analyses revealed that BMAT is distinct from WAT and BAT, with altered glucose metabolism and decreased insulin responsiveness. We therefore tested these functions in mice and humans using positron emission tomography-computed tomography (PET/CT) with
Indexed as
Adipose Tissue, BrownAdipose Tissue, WhiteAnimalsBlotting, WesternBone MarrowFemaleGlucoseHomeostasisHumansMaleMiceMice, Inbred C57BLPositron-Emission TomographyRatsSkeletonGlucose
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What OpenQuestion holds
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.