Evidence map›Paper›PMID 32554724›Full record

ArticleBMJ open2020

Feasibility randomised controlled trial of remote symptom chemotherapy toxicity monitoring using the Canadian adapted Advanced Symptom Management System (ASyMS-Can): a study protocol.

Saeed Moradian, Monika Krzyzanowska, Roma Maguire, Vishal Kukreti, Eitan Amir, Plinio P Morita, Geoffrey Liu, Doris Howell

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03335189 (Adaptation, Feasibility and Acceptability Study of the Advanced Symptom Management System), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03335189 nacompletednot on this map

Adaptation, Feasibility and Acceptability Study of the Advanced Symptom Management System (ASyMS) Mobile Health Intervention to Reduce Chemotherapy Toxicities in Canadian Cancer Patients

TypeinterventionalSponsorUniversity Health Network, TorontoRan2017 to 2019Enrolled84ConditionsSupportive Care, CancerArmsASyMS-Can
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Saeed MoradianSchool of Nursing, York University Faculty of Health, Toronto, Ontario, Canada.ORCID 0000-0002-5289-4806
Monika KrzyzanowskaUniversity of Toronto Institute of Health Policy Management and Evaluation, Toronto, Ontario, Canada.
Roma MaguireUniversity of Strathclyde Department of Computer and Information Sciences, Glasgow, UK.
Vishal KukretiDivision of Medical Oncology and Hematology, University of Toronto Faculty of Medicine, Toronto, Ontario, Canada.
Eitan AmirDepartment of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Plinio P MoritaSchool of Public Health and Health Systems, University of Waterloo, Waterloo, ON, Canada.
Geoffrey LiuUniversity Health Network and Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
Doris HowellDepartment of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada doris.howell@uhn.ca.
University Health Network · CAUniversity of Strathclyde · GBUniversity of Toronto · CAUniversity of Waterloo · CAYork University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTechnology is emerging as a solution to develop home-based, proactive 'real-time' symptom monitoring and management in cancer care. The Advanced Symptom Monitoring and Management System-Canada (ASyMS-Can) is a remote phone-based symptom management system that enables real-time remote monitoring of systemic chemotherapy toxicities. METHODS AND ANALYSIS: This study is an open-label, prospective, mixed-method, Phase II, 2-arm parallel group assignment (ASyMS-Can vs usual care) feasibility study in patients with cancer receiving systemic (neo-adjuvant or adjuvant) chemotherapy at Princess Margaret Cancer Centre. A total of 114 patients will be recruited in oncology clinics prior to initiation of chemotherapy. Patients in both arms will complete a demographic and a set of questionnaires at enrolment, mid and end of treatment. Patients in intervention arm will be provided with an encrypted, secure, preprogrammed ASyMS phone for symptom reporting daily for the first 14 days of each chemotherapy treatment cycle up to sixth cycle (16 weeks). Feasibility metrics (recruitment, retention and protocol adherence) and outcomes to assess impact of ASyMS-Can include symptom severity, emotional distress, quality of life and acceptability to patients and clinicians. ETHICS AND DISSEMINATION: The study has received ethical and institutional approvals from the University Health Network. Dissemination will include presentations at national/international conferences, and publications in peer-reviewed journals. TRIAL REGISTRATION NUMBER: NCT03335189.

Indexed as

Symptom AssessmentAntineoplastic AgentsDrug MonitoringFeasibility StudiesHumansNeoplasmsOntarioProspective StudiesRandomized Controlled Trials as TopicResearch DesignTelephoneAntineoplastic Agentsadult oncologytelemedicineworld wide web technology

Identifiers

PMID32554724
PMCPMC7313714
OpenAlexW3036763399

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.