Evidence map›Paper›PMID 32554530›Full record

ArticleDevelopment (Cambridge, England)2020

Development and function of smooth muscle cells is modulated by

Aya Uchida, Sadman Sakib, Elodie Labit, Sepideh Abbasi, R Wilder Scott, T Michael Underhill, Jeff Biernaskie, Ina Dobrinski

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Characterization ofBiomolecules · 2026
    Article
  2. Article
  3. Article
  4. Sertoli cells as a hub in testicular development and male reproductive.Frontiers in cell and developmental biology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Oncotarget · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Aya UchidaDepartment of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada.ORCID 0000-0001-5000-266X
Sadman SakibDepartment of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada.ORCID 0000-0002-3864-7999
Elodie LabitDepartment of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada.ORCID 0000-0002-7659-6248
Sepideh AbbasiDepartment of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
R Wilder ScottThe Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
T Michael UnderhillThe Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
Jeff BiernaskieDepartment of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
Ina DobrinskiDepartment of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada idobrins@ucalgary.ca.ORCID 0000-0002-0695-2606
University of Calgary · CAUniversity of British Columbia · CA

Funding

Transplantation of Testis Stem Cells in Large AnimalsR01OD016575 · OD · UNIVERSITY OF CALGARY · PI DOBRINSKI, INA · 2013 to 2024
$2.4M
iPSC-derived Organoids to Study Testis FunctionR01HD091068 · NICHD · UNIVERSITY OF CALGARY · PI DOBRINSKI, INA · 2017 to 2019
$837k
NICHD NIH HHS R01 HD091068NIH HHS R01 OD016575
6 · The paper itself

Abstract

In mammalian testis, contractile peritubular myoid cells (PMCs) regulate the transport of sperm and luminal fluid, while secreting growth factors and extracellular matrix proteins to support the spermatogonial stem cell niche. However, little is known about the role of testicular smooth muscle cells during postnatal testicular development. Here we report age-dependent expression of hypermethylated in cancer 1 (

Indexed as

ActinsAnimalsFibronectinsKruppel-Like Transcription FactorsMaleMicrofilament ProteinsMyocytes, Smooth MuscleTestisActinsFibronectinsKruppel-Like Transcription FactorsMicrofilament ProteinsFibronectinHic1MousePeritubular myoid cellTesticular smooth muscle cellsTestis

Identifiers

PMID32554530
PMCPMC7375483
OpenAlexW3036066449

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.