Evidence map›Paper›PMID 32554521›Full record

ArticlePediatrics2020

Global Burden of Childhood Epilepsy, Intellectual Disability, and Sensory Impairments.

Bolajoko O Olusanya, Scott M Wright, M K C Nair, Nem-Yun Boo, Ricardo Halpern, Hannah Kuper, Amina A Abubakar, Nihad A Almasri, Jalal Arabloo, Narendra K Arora and 26 more

Abstract read
In one paragraph

Article in Pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Clinical and genetic characterization of intellectual disability.Developmental medicine and child neurology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

36 authors.

Bolajoko O OlusanyaCentre for Healthy Start Initiative, Lagos, Nigeria; bolajoko.olusanya@uclmail.net.
Scott M WrightDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
M K C NairNIMS Spectrum Child Development Research Centre, NIMS Medicity, Thiruvananthapuram, Kerala, India.
Nem-Yun BooDepartment of Population Medicine, Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Selangor, Malaysia.
Ricardo HalpernDepartment of Pediatrics and Adolescence, University of Health Sciences of Porto Alegre, Porto Alegrel, Brazil.
Hannah KuperInternational Centre for Evidence in Disability, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Amina A AbubakarKenya Medical Research Institute-Wellcome Trust Research Programme, Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute, KiIifi, Kenya.
Nihad A AlmasriDepartment of Physiotherapy, School of Rehabilitation Sciences, The University of Jordan, Amman, Jordan.
Jalal ArablooHealth Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran.
Narendra K AroraThe INCLEN Trust International, New Delhi, India.
Sophia BackhausCentre for Evidence-Based Intervention, Department of Social Policy and Intervention, University of Oxford, Oxford, United Kingdom.
Brad D BermanDepartment of Pediatrics, University of California, San Francisco Benioff Children's Hospital, San Francisco, California.
Cecilia BreinbauerCenter for Healthy Development, Seattle, Washington.
Gwen CarrEar Institute, University College London, London, United Kingdom.
Petrus J de VriesDivision of Child and Adolescent Psychiatry, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.
Christie Del Castillo-HegyiDepartment of Emergency Medicine, CHI St. Vincent, Little Rock, Arkansas.
Aziz EftekhariDepartment of Pharmacology and Toxicology, Maragheh University of Medical Sciences, Maragheh, Iran.
Melissa J GladstoneInstitute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.
Rosa A HoekstraDepartment of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Vijaya KancherlaDepartment of Epidemiology, Emory University Rollins School of Public Health, Atlanta, Georgia.
Mphelekedzeni C MulaudziDepartment of Paediatrics and Child Health, University of the Witwatersrand, Johannesburg, Johannesburg, South Africa.
Angelina Kakooza-MwesigeDepartment of Paediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda.
Felix A OgboTranslational Health Research Institute, School of Medicine, Western Sydney University, Campbelltown Campus, Penrith, New South Wales, Australia.
Helen E OlsenBill and Melinda Gates Foundation, Seattle, Washington.
Jacob O OlusanyaCentre for Healthy Start Initiative, Lagos, Nigeria; bolajoko.olusanya@uclmail.net.
Ashok PandeyNepal Health Research Council, Kathmandu, Nepal.
Maureen E Samms-VaughanDepartment of Child and Adolescent Health, The University of the West Indies, Mona Campus, Kingston, Jamaica.
Chiara ServiliDepartment of Mental Health and Substance Use, World Health Organization, Geneva, Switzerland.
Amira ShaheenDivision of Public Health, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Tracey SmytheInternational Centre for Evidence in Disability, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Donald WertliebEliot-Pearson Department of Child Development, Tufts University, Medford, Massachusetts.
Andrew N WilliamsVirtual Academic Unit, Northampton General Hospital, Northampton, United Kingdom; and.
Charles R J NewtonKenya Medical Research Institute-Wellcome Trust Research Programme, Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute, KiIifi, Kenya.
Adrian C DavisEar Institute, University College London, London, United Kingdom.
Nicholas J KassebaumInstitute for Health Metrics and Evaluation, University of Washington, Seattle, Washington.
Global Research on Developmental Disabilities Collaborators (GRDDC)

Funding

Wellcome Trust 203077
6 · The paper itself

Abstract

backgroundEstimates of children and adolescents with disabilities worldwide are needed to inform global intervention under the disability-inclusive provisions of the Sustainable Development Goals. We sought to update the most widely reported estimate of 93 million children <15 years with disabilities from the Global Burden of Disease Study 2004.

methodsWe analyzed Global Burden of Disease Study 2017 data on the prevalence of childhood epilepsy, intellectual disability, and vision or hearing loss and on years lived with disability (YLD) derived from systematic reviews, health surveys, hospital and claims databases, cohort studies, and disease-specific registries. Point estimates of the prevalence and YLD and the 95% uncertainty intervals (UIs) around the estimates were assessed.

resultsGlobally, 291.2 million (11.2%) of the 2.6 billion children and adolescents (95% UI: 249.9-335.4 million) were estimated to have 1 of the 4 specified disabilities in 2017. The prevalence of these disabilities increased with age from 6.1% among children aged <1 year to 13.9% among adolescents aged 15 to 19 years. A total of 275.2 million (94.5%) lived in low- and middle-income countries, predominantly in South Asia and sub-Saharan Africa. The top 10 countries accounted for 62.3% of all children and adolescents with disabilities. These disabilities accounted for 28.9 million YLD or 19.9% of the overall 145.3 million (95% UI: 106.9-189.7) YLD from all causes among children and adolescents.

conclusionsThe number of children and adolescents with these 4 disabilities is far higher than the 2004 estimate, increases from infancy to adolescence, and accounts for a substantial proportion of all-cause YLD.

Indexed as

AdolescentBlindnessChildChild, PreschoolEpilepsyFemaleGlobal Burden of DiseaseHearing LossHumansInfantIntellectual DisabilityMalePrevalenceYoung Adult

Identifiers

PMID32554521
PMCPMC7613313

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.