Evidence map›Paper›PMID 32554481›Full record

ArticleBiology open2020

Communication between Cyclin-dependent kinase Cdc2 and the Wis1-Spc1 MAPK pathway determines mitotic timing in

Agamani Ghosal, Priyanka Sarkar, Geetanjali Sundaram

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Agamani GhosalDepartment of Biochemistry, University of Calcutta, 35, Ballygunge Circular Road, Kolkata, 700019, WB, India.ORCID 0000-0001-5121-3557
Priyanka SarkarDepartment of Biochemistry, University of Calcutta, 35, Ballygunge Circular Road, Kolkata, 700019, WB, India.ORCID 0000-0001-9234-2005
Geetanjali SundaramDepartment of Biochemistry, University of Calcutta, 35, Ballygunge Circular Road, Kolkata, 700019, WB, India geetanjali.sundaram@gmail.com.ORCID 0000-0003-4819-5444
University of Calcutta · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Checkpoint activation and gene expression modulation represent key determinants of cellular survival in adverse conditions. The former is regulated by cyclin-dependent kinases (CDKs) while the latter can be controlled by mitogen-activated protein kinases (MAPKs). Association between cell-cycle progression and MAPK-dependent gene expression exists in cells growing in optimal environments. While MAPK-mediated regulation of the cell cycle is well characterised, the reciprocal influence of mitotic CDK on stress response is not well studied. We present evidence that CDK activity can regulate the extent of MAPK activation in

Indexed as

Signal TransductionCDC2 Protein KinaseGene Expression Regulation, FungalMitogen-Activated Protein Kinase KinasesMitogen-Activated Protein KinasesMitosisModels, BiologicalPhosphorylationSchizosaccharomycesSchizosaccharomyces pombe ProteinsStress, PhysiologicalCDC2 Protein KinaseMitogen-Activated Protein Kinase KinasesMitogen-Activated Protein KinasesSchizosaccharomyces pombe ProteinsSpc1 protein, S pombewis1 protein, S pombeCdc2MitosisRad24Spc1S. pombeWis1

Identifiers

PMID32554481
PMCPMC7390630
OpenAlexW3036045210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.