Evidence map›Paper›PMID 32554419›Full record

ArticleAJNR. American journal of neuroradiology2020

A Hemodynamic Mechanism Correlating with the Initiation of MCA Bifurcation Aneurysms.

Z Huang, M Zeng, W G Tao, F Y Zeng, C Q Chen, L B Zhang, F H Chen

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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  6. Integrative analysis of multi-omics data to identify three immune-related genes in the formation and progression of intracranial aneurysms.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Z HuangFrom the Departments of Neurosurgery (Z.H., M.Z., F.H.C., W.G.T.).ORCID 0000-0003-0648-3499
M ZengFrom the Departments of Neurosurgery (Z.H., M.Z., F.H.C., W.G.T.).ORCID 0000-0002-8373-4709
W G TaoFrom the Departments of Neurosurgery (Z.H., M.Z., F.H.C., W.G.T.).ORCID 0000-0003-3786-6708
F Y ZengRadiology (F.Y.Z., C.Q.C.), Xiangya Hospital, Central South University, Changsha, China.ORCID 0000-0002-5322-3123
C Q ChenRadiology (F.Y.Z., C.Q.C.), Xiangya Hospital, Central South University, Changsha, China.ORCID 0000-0001-8313-6322
L B ZhangDepartment of Neurosurgery (L.B.Z.), School of Medicine, Yale University, New Haven, Connecticut.ORCID 0000-0002-9077-3239
F H ChenFrom the Departments of Neurosurgery (Z.H., M.Z., F.H.C., W.G.T.) xyswcfh@csu.edu.cn.ORCID 0000-0002-4462-0880
Hi-Z Technology (United States) · USCentral South University · CNYale University · USZTE (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposePrevious studies have reported that MCA bifurcation aneurysms usually emerge on inclined bifurcations; however, the reason is unclear. We designed this study to explore hemodynamic mechanisms that correlate with the initiation of MCA bifurcation aneurysms. MATERIALS AND

methodsFifty-four patients with unilateral MCA bifurcation aneurysms and 54 control patients were enrolled in this study after propensity score matching, and their clinical and CTA data were collected. We extracted the morphologic features of aneurysmal MCA bifurcations to build a simplified MCA bifurcation model and performed a computational fluid dynamics analysis.

resultsThe presence of MCA aneurysms correlated with smaller parent-daughter angles of MCA bifurcations (

conclusionsOur results suggest that the initiation of MCA bifurcation aneurysms may correlate with shifts of high-pressure regions and low wall shear stress regions that occur on inclined MCA bifurcations.

Indexed as

AdultCerebral AngiographyComputed Tomography AngiographyFemaleHemodynamicsHumansHydrodynamicsIntracranial AneurysmMaleMiddle AgedMiddle Cerebral ArteryStress, Mechanical

Identifiers

PMID32554419
PMCPMC7357637
OpenAlexW3036431228

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.