Evidence map›Paper›PMID 32553165›Full record

ArticleCell reports2020

Identification of a G-Protein-Independent Activator of GIRK Channels.

Yulin Zhao, Peter Man-Un Ung, Gergely Zahoránszky-Kőhalmi, Alexey V Zakharov, Natalia J Martinez, Anton Simeonov, Ian W Glaaser, Ganesha Rai, Avner Schlessinger, Juan J Marugan and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Article
  3. Subthreshold Kir and IBiological research · 2026
    Article
  4. Article
  5. G protein-gated inwardly rectifying KHistology and histopathology · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Upregulated GIRK2 Counteracts Ethanol-Induced Changes in Excitability and Respiration in Human Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Neuronal G protein-gated KAmerican journal of physiology. Cell physiology · 2022
    Review
  16. Article
  17. AsKC11, a Kunitz Peptide fromMarine drugs · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yulin ZhaoNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Peter Man-Un UngDepartment of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Gergely Zahoránszky-KőhalmiNational Center for Advancing Translational Sciences (NCATS), Rockville, MD 20850, USA.
Alexey V ZakharovNational Center for Advancing Translational Sciences (NCATS), Rockville, MD 20850, USA.
Natalia J MartinezNational Center for Advancing Translational Sciences (NCATS), Rockville, MD 20850, USA.
Anton SimeonovNational Center for Advancing Translational Sciences (NCATS), Rockville, MD 20850, USA.
Ian W GlaaserNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Ganesha RaiNational Center for Advancing Translational Sciences (NCATS), Rockville, MD 20850, USA.
Avner SchlessingerDepartment of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Juan J MaruganNational Center for Advancing Translational Sciences (NCATS), Rockville, MD 20850, USA.
Paul A SlesingerNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: paul.slesinger@mssm.edu.
National Center for Advancing Translational Sciences · USIcahn School of Medicine at Mount Sinai · US

Funding

Structural Analysis of Alcohol-dependent Activation of GIRKsR01AA018734 · NIAAA · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Paul A Slesinger · 2010 to 2026
$6.6M
Substrate Specificity Determinants in Nutrient Solute Carrier TransportersR01GM108911 · NIGMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SCHLESSINGER, AVNER · 2014 to 2022
$3.1M
NIAAA NIH HHS R01 AA018734NIGMS NIH HHS R01 GM108911
6 · The paper itself

Abstract

G-protein-gated inwardly rectifying K

Indexed as

AnimalsBrainEpilepsyG Protein-Coupled Inwardly-Rectifying Potassium ChannelsGTP-Binding ProteinsIon Channel GatingMice, KnockoutNeuronsG Protein-Coupled Inwardly-Rectifying Potassium ChannelsGTP-Binding Proteinsalcohol-like kineticsantiseizureepilepsyGIRK1-selective activatorG-protein-gated inwardly rectifying K(+) channel

Identifiers

PMID32553165
PMCPMC7401321
OpenAlexW3036846747

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.