ArticleCell chemical biology2020
tRNA
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Article in Cell chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
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Who cites it
23 citing papers in PubMed, 29 citations in OpenAlex.
- Tracing the mark of arginine.Nature chemical biology · 2025Article
- Transfer RNA regulation during herpesvirus infection: Wielding a sword or raising a shield?PLoS pathogens · 2025Article
- Identification of an Intrinsically Disordered Region (IDR) in Arginyltransferase 1 (ATE1).Biochemistry · 2024Article
- An atlas of small non-coding RNAs in human preimplantation development.Nature communications · 2024Article
- Copper catalyzed cycloaddition for the synthesis of non isomerisable 2' and 3'-regioisomers of arg-tRNAMethods (San Diego, Calif.) · 2024Article
- Identification of an intrinsically disordered region (IDR) in arginyltransferase 1 (ATE1).bioRxiv : the preprint server for biology · 2024Article
- Oligomerization and a distinct tRNA-binding loop are important regulators of human arginyl-transferase function.Nature communications · 2024Article
- The structural basis of tRNA recognition by arginyl-tRNA-protein transferase.Nature communications · 2023Article
- The role and mechanism of action of tRNA-derived fragments in the diagnosis and treatment of malignant tumors.Cell communication and signaling : CCS · 2023Review
- Enzymatic Aminoacylation of tRNAMethods in molecular biology (Clifton, N.J.) · 2023Article
- The preparation of recombinant arginyltransferase 1 (ATE1) for biophysical characterization.Methods in enzymology · 2023Article
- Synthesis of Peptides and Proteins with Site-Specific Glutamate Arginylation.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Synthesis of Stably Charged Arg-tRNAMethods in molecular biology (Clifton, N.J.) · 2023Article
- The Structure of Saccharomyces cerevisiae Arginyltransferase 1 (ATE1).Journal of molecular biology · 2022Article
- Functional Interplay between Arginyl-tRNA Synthetases and Arginyltransferase.International journal of molecular sciences · 2022Article
- Crystal structure of the Ate1 arginyl-tRNA-protein transferase and arginylation of N-degron substrates.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Structural basis for impaired 5' processing of a mutant tRNA associated with defects in neuronal homeostasis.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Availability of Arg, but Not tRNA, Is a Rate-Limiting Factor for Intracellular Arginylation.International journal of molecular sciences · 2021Article
- Origins and evolving functionalities of tRNA-derived small RNAs.Trends in biochemical sciences · 2021Review
- ATE1-Mediated Post-Translational Arginylation Is an Essential Regulator of Eukaryotic Cellular Homeostasis.ACS chemical biology · 2020Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Irem Avcilar-KucukgozeDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Howard GamperDepartment of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19144, USA.
Christine PolteInstitute of Biochemistry and Molecular Biology, University of Hamburg, 20148 Hamburg, Germany.
Zoya IgnatovaInstitute of Biochemistry and Molecular Biology, University of Hamburg, 20148 Hamburg, Germany.
Ralph KraetznerDepartment of Pediatrics and Adolescent Medicine, University Medical Center Göttingen, 37075 Göttingen, Germany.
Michael ShtutmanDepartment of Drug Discovery and Biomedical Sciences, College of Pharmacy, University of South Carolina, Columbia, SC 29208, USA.
Ya-Ming HouDepartment of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19144, USA.
Dawei W DongDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Anna KashinaDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: akashina@upenn.edu.
University of Pennsylvania · USThomas Jefferson University · USUniversität Hamburg · DEUniversitätsmedizin Göttingen · DEUniversity of South Carolina · US
Funding
Targeting NMDA Receptors and Brain Estradiol to Rescue Memory in Aging FemalesP20GM109091 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI RONINSON, IGOR B · 2014 to 2024
$25.2MRegulation of cell migration by nucleotide coding sequence and arginylationR35GM122505 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Anna S Kashina · 2017 to 2026
$6.2MtRNA in codon usageR35GM134931 · NIGMS · THOMAS JEFFERSON UNIVERSITY · PI HOU, YA-MING · 2020 to 2025
$5.4MRole of arginylation in prevention of alpha synuclein-driven neurodegenerationR01NS102435 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI KASHINA, ANNA S · 2019 to 2023
$2.6MDiscovery of Gram-negative permeable chemical probes for tRNA methylationR01AI139202 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI HOU, YA-MING · 2019 to 2022
$2.4MProbe discovery for tRNA methylationR01GM126210 · NIGMS · THOMAS JEFFERSON UNIVERSITY · PI HOU, YA-MING, SMITH, LAYTON HARRIS · 2018 to 2020
$1.2MMining the tRNA genome by live-cell imagingR21HG010824 · NHGRI · THOMAS JEFFERSON UNIVERSITY · PI AHERN, CHRISTOPHER A, HOU, YA-MING · 2019 to 2020
$441kImpact of Dead Box RNA Helicase 3 signaling on HIV-1 Tat- and cocaine-induced neurotoxicityR21DA047936 · NIDA · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI SHTUTMAN, MICHAEL, WYATT, MICHAEL D. · 2019 to 2020
$408kNHGRI NIH HHS R21 HG010824NIAID NIH HHS R01 AI139202NIDA NIH HHS R21 DA047936NIGMS NIH HHS P20 GM109091NIGMS NIH HHS R01 GM126210NIGMS NIH HHS R35 GM122505NIGMS NIH HHS R35 GM134931NINDS NIH HHS R01 NS102435
Abstract
Arginyltransferase ATE1 mediates posttranslational arginylation and plays key roles in multiple physiological processes. ATE1 utilizes arginyl (Arg)-tRNA
Indexed as
AminoacyltransferasesAngiotensin IIAnimalsArginineCell LineHumansMiceProtein BindingProtein Processing, Post-TranslationalRNA, Transfer, ArgSubstrate SpecificityAminoacyltransferasesAngiotensin IIArginineAte1 protein, mouseRNA, Transfer, ArgarginylationtRFtRNA
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.