Evidence map›Paper›PMID 32552920›Full record

ArticleBJPsych open2020

General practitioners' and psychiatrists' attitudes towards antidepressant withdrawal.

Joanne McCabe, Mike Wilcock, Kate Atkinson, Richard Laugharne, Rohit Shankar

Abstract read
In one paragraph

Article in BJPsych open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. The lived experience of withdrawal from Selective Serotonin Reuptake Inhibitor (SSRI) antidepressants: A qualitative interview study.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
  2. Article
  3. Designing Flexible Longitudinal Regimens: Supporting Clinician Planning for Discontinuation of Psychiatric Drugs.Proceedings of the SIGCHI conference on human factors in computing systems. CHI Conference · 2022
    Article
  4. Yonder: COVID non-compliance, antidepressant withdrawal, probiotics, and GPs in China.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joanne McCabeUniversity of Exeter Medical School Knowledge Spa, Royal Cornwall Hospital, Truro, UK.
Mike WilcockRoyal Cornwall Hospitals NHS Trust, Treliske, Truro, UK.
Kate AtkinsonCornwall Partnership NHS Foundation Trust, Truro, UK.
Richard LaugharneUniversity of Exeter Medical School Knowledge Spa, Royal Cornwall Hospital, Truro; and Caradon CMHT, Trevillis House, Lodge Hill, Cornwall Partnership NHS Foundation Trust, Truro, UK.ORCID https://orcid.org/0000-0001-9916-343X
Rohit ShankarUniversity of Exeter Medical School Knowledge Spa, Royal Cornwall Hospital, Truro; and Adult ID, Neurodevelopmental services Truro, Cornwall Partnership NHS Foundation Trust, Truro, UK.ORCID https://orcid.org/0000-0002-1183-6933

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere has been a recent rise in antidepressant prescriptions. After the episode for which it was prescribed, the patient should ideally be supported in withdrawing the medication. There is increasing evidence for withdrawal symptoms (sometimes called discontinuation symptoms) occurring on ceasing treatment, sometimes having severe or prolonged effects.

aimsTo identify and compare current knowledge, attitudes and practices of general practitioners (GPs) and psychiatrists in Cornwall, UK, concerning antidepressant withdrawal symptoms.

methodQuestions about withdrawal symptoms and management were asked of GPs and psychiatrists in a multiple-choice cross-sectional study co-designed with a lived experience expert.

resultsPsychiatrists thought that withdrawal symptoms were more severe than GPs did (P = 0.003); 53% (22/42) of GPs and 69% (18/26) of psychiatrists thought that withdrawal symptoms typically last between 1 and 4 weeks, although there was a wide range of answers given; 35% (9/26) of psychiatrists but no GPs identified a pharmacist as someone they may use to help manage antidepressant withdrawal. About three-quarters of respondents claimed they usually or always informed patients of potential withdrawal symptoms when they started a patient on antidepressants, but patient surveys say only 1% are warned.

conclusionsPsychiatrists and GPs need to effectively warn patients of potential withdrawal effects. Community pharmacists might be useful in supporting GP-managed antidepressant withdrawal. The wide variation in responses to most questions posed to participants reflects the variation in results of research on the topic. This highlights a need for more reproducible studies to be carried out on antidepressant withdrawal, which could inform future guidelines.

Indexed as

Antidepressantspublic mental healthpublic opinionwithdrawal side-effects

Identifiers

PMID32552920
PMCPMC7345735

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.