Evidence map›Paper›PMID 32552725›Full record

ArticleGenome biology2020

KAML: improving genomic prediction accuracy of complex traits using machine learning determined parameters.

Lilin Yin, Haohao Zhang, Xiang Zhou, Xiaohui Yuan, Shuhong Zhao, Xinyun Li, Xiaolei Liu

Abstract readEvaluation Study
In one paragraph

Article in Genome biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Genome-Enabled Prediction Methods Based on Machine Learning.Methods in molecular biology (Clifton, N.J.) · 2022
    Pooled it
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  8. Impact of scale parameter for marker variance prior in some Bayesian whole-genome regression methods.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lilin YinKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education & College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, 430070, Hubei, People's Republic of China.
Haohao ZhangSchool of Computer Science and Technology, Wuhan University of Technology, Wuhan, 430070, China.
Xiang ZhouDepartment of Biostatistics, University of Michigan, Ann Arbor, MI, USA.
Xiaohui YuanSchool of Computer Science and Technology, Wuhan University of Technology, Wuhan, 430070, China.
Shuhong ZhaoKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education & College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, 430070, Hubei, People's Republic of China.
Xinyun LiKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education & College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, 430070, Hubei, People's Republic of China. xyli@mail.hzau.edu.cn.
Xiaolei LiuKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education & College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, 430070, Hubei, People's Republic of China. xiaoleiliu@mail.hzau.edu.cn.ORCID 0000-0002-9954-1426

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in high-throughput sequencing technologies have reduced the cost of genotyping dramatically and led to genomic prediction being widely used in animal and plant breeding, and increasingly in human genetics. Inspired by the efficient computing of linear mixed model and the accurate prediction of Bayesian methods, we propose a machine learning-based method incorporating cross-validation, multiple regression, grid search, and bisection algorithms named KAML that aims to combine the advantages of prediction accuracy with computing efficiency. KAML exhibits higher prediction accuracy than existing methods, and it is available at https://github.com/YinLiLin/KAML.

Indexed as

Machine LearningModels, GeneticQuantitative Trait, HeritableSoftwareAnimalsCattleGenomicsHumansModels, Statistical

Identifiers

PMID32552725
PMCPMC7386246

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.