ArticleJournal of applied physiology (Bethesda, Md. : 1985)2020
Neutralizing mitochondrial ROS does not rescue muscle atrophy induced by hindlimb unloading in female mice.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 36 citations in OpenAlex.
- Mitochondrial Impairment in Unloaded Postural Muscle: Mechanisms Driving Loss of Muscle Function and Mass.Antioxidants (Basel, Switzerland) · 2026Review
- Effects of Voluntary Exercise and Acetic Acid Supplementation on Skeletal Muscle Mitochondrial Function in Ovariectomized Mice.Nutrients · 2026Article
- Noninvasive PET imaging of LPS-induced oxidative stress in skeletal muscle using a ROS-targeting radiotracer.Scientific reports · 2026Article
- N-acetylcarnosine attenuates age-associated declines in multi-organ systems to improve survival.bioRxiv : the preprint server for biology · 2025Article
- Inhibition of mitochondrial fission protein Drp1 ameliorates skeletal myopathy in the D2-mdx model of Duchenne muscular dystrophy.American journal of physiology. Cell physiology · 2025Article
- Muscle-specific Keap1 deletion enhances force production but does not prevent inactivity-induced muscle atrophy in mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- Mechanotransduction and Skeletal Muscle Atrophy: The Interplay Between Focal Adhesions and Oxidative Stress.International journal of molecular sciences · 2025Review
- Effects of Vitamin E Intake and Voluntary Wheel Running on Whole-Body and Skeletal Muscle Metabolism in Ovariectomized Mice.Nutrients · 2025Article
- Muscle structure assessment using synchrotron radiation X-ray micro-computed tomography in murine with cerebral ischemia.Scientific reports · 2024Article
- Inhibition of the skeletal muscle Lands cycle ameliorates weakness induced by physical inactivity.Journal of cachexia, sarcopenia and muscle · 2024Article
- Lipid peroxidation does not mediate muscle atrophy induced by PSD deficiency.bioRxiv : the preprint server for biology · 2023Article
- Sex differences in muscle health in simulated micro- and partial-gravity environments in rats.Sports medicine and health science · 2023Article
- Global deletion of CCL2 has adverse impacts on recovery of skeletal muscle fiber size and function and is muscle specific.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Article
- Article
- Mitochondrial Dysfunction in Intensive Care Unit-Acquired Weakness and Critical Illness Myopathy: A Narrative Review.International journal of molecular sciences · 2023Review
- Chicken or Egg? Mitochondrial Phospholipids and Oxidative Stress in Disuse-Induced Skeletal Muscle Atrophy.Antioxidants & redox signaling · 2023Review
- Exercise and mitochondrial mechanisms in patients with sarcopenia.Frontiers in physiology · 2022Review
- Characterizing SERCA Function in Murine Skeletal Muscles after 35-37 Days of Spaceflight.International journal of molecular sciences · 2021Article
- Low lysophosphatidylcholine induces skeletal muscle myopathy that is aggravated by high-fat diet feeding.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021Article
- Systemic delivery of a mitochondria targeted antioxidant partially preserves limb muscle mass and grip strength in response to androgen deprivation.Molecular and cellular endocrinology · 2021Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
Excess reactive oxygen species (ROS) induced by physical inactivity is associated with muscle atrophy and muscle weakness. However, the role of mitochondrial ROS on disuse-induced muscle atrophy is not fully understood. The purpose of this study was to utilize a genetic strategy to examine the effect of neutralizing mitochondrial ROS on disuse-induced skeletal muscle atrophy. This was accomplished by placing wild-type (WT) and mitochondrial-targeted catalase-expressing (MCAT) littermate mice on 7 days of hindlimb unloading. After assessment of body weight and composition, muscles were analyzed for individual muscle mass, force-generating capacity, fiber type, cross-sectional area, and mitochondrial function, including H
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.