Evidence map›Paper›PMID 32552401›Full record

ArticleGut microbes2020

Dynamic analysis of human small intestinal microbiota after an ingestion of fermented milk by small-intestinal fluid perfusion using an endoscopic retrograde bowel insertion technique.

Toshihiko Takada, Daisuke Chinda, Tatsuya Mikami, Kensuke Shimizu, Kosuke Oana, Shiro Hayamizu, Kuniaki Miyazawa, Tetsu Arai, Miyuki Katto, Yusuke Nagara and 4 more

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Toshihiko TakadaLaboratory of Applied Microbiology, Microbiological Research Department, Yakult Central Institute , Tokyo, Japan.ORCID 0000-0002-9914-8253
Daisuke ChindaLaboratory of Gastroenterology and Hematology, Graduate School of Medicine, Hirosaki University , Aomori, Japan.ORCID 0000-0003-1690-5923
Tatsuya MikamiLaboratory of Gastroenterology and Hematology, Graduate School of Medicine, Hirosaki University , Aomori, Japan.
Kensuke ShimizuLaboratory of Applied Microbiology, Microbiological Research Department, Yakult Central Institute , Tokyo, Japan.
Kosuke OanaLaboratory of Applied Microbiology, Microbiological Research Department, Yakult Central Institute , Tokyo, Japan.
Shiro HayamizuLaboratory of Gastroenterology and Hematology, Graduate School of Medicine, Hirosaki University , Aomori, Japan.
Kuniaki MiyazawaLaboratory of Gastroenterology and Hematology, Graduate School of Medicine, Hirosaki University , Aomori, Japan.
Tetsu AraiLaboratory of Gastroenterology and Hematology, Graduate School of Medicine, Hirosaki University , Aomori, Japan.
Miyuki KattoLaboratory of Applied Microbiology, Microbiological Research Department, Yakult Central Institute , Tokyo, Japan.
Yusuke NagaraLaboratory of Applied Microbiology, Microbiological Research Department, Yakult Central Institute , Tokyo, Japan.
Hiroshi MakinoLaboratory of Applied Microbiology, Microbiological Research Department, Yakult Central Institute , Tokyo, Japan.
Akira KushiroLaboratory of Applied Microbiology, Microbiological Research Department, Yakult Central Institute , Tokyo, Japan.
Kenji OishiLaboratory of Applied Microbiology, Microbiological Research Department, Yakult Central Institute , Tokyo, Japan.
Shinsaku FukudaLaboratory of Gastroenterology and Hematology, Graduate School of Medicine, Hirosaki University , Aomori, Japan.
Yakult Central Institute · JPHirosaki University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotic products have been shown to have beneficial effects on human hosts, but what happens in the gastrointestinal tract after its ingestion remains unclear. Our aim was to investigate the changes within the small intestines after a single intake of a fermented milk product containing a probiotic. We have periodically collected the small-intestinal fluids from the terminal ileum of seven healthy subjects for up to 7 h after ingestion by small-intestinal fluid perfusion using an endoscopic retrograde bowel insertion technique. The bacterial composition of the terminal ileum clearly revealed that the ingested probiotics (

Indexed as

Gastrointestinal MicrobiomeAdultAnimalsBacteriaBody FluidsCattleCultured Milk ProductsEndoscopesHumansIntestine, SmallMaleMicrobial ViabilityMiddle AgedProbioticsYoung AdultBifidobacterium breve strain Yakultcolony-forming abilityendoscopic retrograde bowel insertionfermented milkhumanileal microbiotaLactobacillus casei strain Shirotamicrobiomicsprobioticssmall-intestinal fluid perfusion

Identifiers

PMID32552401
PMCPMC7524281
OpenAlexW3036076665

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.