Evidence map›Paper›PMID 32551948›Full record

ArticleAmerican journal of respiratory and critical care medicine2020

Isoniazid Preventive Therapy in Contacts of Multidrug-Resistant Tuberculosis.

Chuan-Chin Huang, Mercedes C Becerra, Roger Calderon, Carmen Contreras, Jerome Galea, Louis Grandjean, Leonid Lecca, Rosa Yataco, Zibiao Zhang, Megan Murray

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Preventing Multidrug-Resistant Tuberculosis: The Dawn of a New Era.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Review
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  19. Prevention of Multidrug-Resistant Tuberculosis in Close Contacts. Back to the Future?American journal of respiratory and critical care medicine · 2020
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Chuan-Chin HuangDivision of Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts.
Mercedes C BecerraDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts.
Roger CalderonPartners in Health-Socios En Salud Sucursal, Lima, Peru.
Carmen ContrerasPartners in Health-Socios En Salud Sucursal, Lima, Peru.
Jerome GaleaSchool of Social Work, University of South Florida, Tampa, Florida.
Louis GrandjeanWellcome Centre for Clinical Tropical Medicine, Imperial College London, London, United Kingdom.
Leonid LeccaPartners in Health-Socios En Salud Sucursal, Lima, Peru.
Rosa YatacoPartners in Health-Socios En Salud Sucursal, Lima, Peru.
Zibiao ZhangDivision of Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts.
Megan MurrayDivision of Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0003-0443-1986
EsSALUD · PEBrigham and Women's Hospital · USHarvard University · USUniversidad Peruana Cayetano Heredia · PEUniversity of South Florida · US

Funding

Sequencing CoreU19AI109755 · NIAID · HARVARD MEDICAL SCHOOL · PI MURRAY, MEGAN B · 2014 to 2018
$29.1M
Metabolomics Core U19AI111224 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI MOODY, DAVID BRANCH, MURRAY, MEGAN B · 2015 to 2021
$20.4M
Real-time surveillance to support dynamic and predictive models of MDR/XDR TBU19AI076217 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI BECERRA, MERCEDES C · 2007 to 2011
$13.5M
Epidemiology of multidrug-resistant tuberculosis in PeruU01AI057786 · NIAID · HARVARD MEDICAL SCHOOL · PI BECERRA, MERCEDES C · 2009 to 2010
$1.2M
NIAID NIH HHS U01 AI057786NIAID NIH HHS U19 AI076217NIAID NIH HHS U19 AI109755NIAID NIH HHS U19 AI111224
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAge FactorsAnalysis of VarianceChildChild, PreschoolCohort StudiesCommunicable Disease ControlContact TracingFamily CharacteristicsFemaleHumansInfantIsoniazidMalePeruPrevalenceIsoniazidINHINH preventive therapymultidrug-resistant tuberculosistuberculosis

Identifiers

PMID32551948
PMCPMC7560814
OpenAlexW3036327523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.