ArticleAmerican journal of respiratory and critical care medicine2020
Genome-Wide Association Study: Functional Variant rs2076295 Regulates Desmoplakin Expression in Airway Epithelial Cells.
Open access · greenAbstract readComparative Study
In one paragraph
Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29citing papers in PubMed
2.8field-weighted citation impact, top 7% of its field
What it found
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Who cites it
29 citing papers in PubMed, 43 citations in OpenAlex.
- Volume EM reveals desmosome three-dimensional architecture in epithelial cells and tissue models.The Journal of cell biology · 2026Article
- Desmoplakin Mutations in Cardiac Fibroblasts Cause TGFβ1-Mediated Pathological Fibrogenesis in Desmoplakin Cardiomyopathy Via Beclin-1 Regulation.Circulation research · 2026Article
- Desmoplakin loss in alveolar epithelium drives Wnt/β-Catenin-mediated extracellular matrix remodeling and fibrotic signaling in vitro.Molecular biology reports · 2026Article
- Identifying expression and DNA methylation biomarkers for lung adenocarcinoma risk in East Asia.Journal of the National Cancer Institute · 2026Article
- Recent advances in pulmonary fibrosis: from lung surfactant to the immune connection.Respiratory research · 2026Review
- SYISL promotes pulmonary epithelial-mesenchymal transition and fibrosis through DSP-Hippo/YAP pathway.Cellular and molecular life sciences : CMLS · 2026Article
- Multi-omics approaches in idiopathic pulmonary fibrosis: from molecular mechanisms to therapeutic targets and precision medicine.Frontiers in pharmacology · 2026Review
- Association Between Single Nucleotide Polymorphisms and Disease Susceptibility, Survival, and Acute Exacerbation in Idiopathic Pulmonary Fibrosis.Respirology (Carlton, Vic.) · 2026Observational
- The Diminution of R-Loops Generated by LncRNA DSP-AS1 Inhibits DSP Gene Transcription to Impede the Re-Epithelialization During Diabetic Wound Healing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Genetic Variants in Genes Related to Lung Function and Interstitial Lung Diseases Are Associated with Worse Outcomes in Severe COVID-19 and Lung Performance in the Post-COVID-19 Condition.International journal of molecular sciences · 2025Article
- Progressive lung fibrosis: reprogramming a genetically vulnerable bronchoalveolar epithelium.The Journal of clinical investigation · 2025Review
- An Overview of the Role of Genetic factors in Idiopathic Pulmonary Fibrosis: Insights from Epidemiology to Prognosis.International journal of medical sciences · 2025Review
- Genetics and Genomics of Pulmonary Fibrosis: Charting the Molecular Landscape and Shaping Precision Medicine.American journal of respiratory and critical care medicine · 2024Review
- Breathing new life into the study of COPD with genes identified from genome-wide association studies.European respiratory review : an official journal of the European Respiratory Society · 2024Review
- Microbial Metagenomes and Host Transcriptomes Reveal the Dynamic Changes of Rumen Gene Expression, Microbial Colonization and Co-Regulation of Mineral Element Metabolism in Yaks from Birth to Adulthood.Animals : an open access journal from MDPI · 2024Article
- Bronchial epithelial gene expression and interstitial lung abnormalities.Respiratory research · 2023Article
- Distinct COPD subtypes in former smokers revealed by gene network perturbation analysis.Respiratory research · 2023Article
- Novel diagnostic techniques in interstitial lung disease.Frontiers in medicine · 2023Review
- Idiopathic Pulmonary Fibrosis Genetic Risk Factors, Function, and Mechanisms? The Concepts Are Starting to Gel.American journal of respiratory and critical care medicine · 2022Article
- Colocalization of Gene Expression and DNA Methylation with Genetic Risk Variants Supports Functional Roles ofAmerican journal of respiratory and critical care medicine · 2022Article
Corrections and comments
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Authors and funding
19 authors at 3 institutions in 1 country.
Yuan HaoChanning Division of Network Medicine and.
Samuel BatesChanning Division of Network Medicine and.
Hongmei MouMucosal Immunology and Biology Research Center, Massachusetts General Hospital, Boston, Massachusetts; and.ORCID 0000-0002-6624-7757
Jeong H YunChanning Division of Network Medicine and.ORCID 0000-0002-4361-8295
Betty PhamChanning Division of Network Medicine and.
Jiangyuan LiuChanning Division of Network Medicine and.
Weiliang QiuChanning Division of Network Medicine and.
Feng GuoChanning Division of Network Medicine and.
Jarrett D MorrowChanning Division of Network Medicine and.
Craig P HershChanning Division of Network Medicine and.ORCID 0000-0002-1342-4334
Christopher J BenwayChanning Division of Network Medicine and.
Lu GongChanning Division of Network Medicine and.
Yihan ZhangMucosal Immunology and Biology Research Center, Massachusetts General Hospital, Boston, Massachusetts; and.
Ivan O RosasDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Michael H ChoChanning Division of Network Medicine and.
Jin-Ah ParkDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Peter J CastaldiChanning Division of Network Medicine and.
Fei DuChanning Division of Network Medicine and.
Xiaobo ZhouChanning Division of Network Medicine and.ORCID 0000-0002-7127-2869
Brigham and Women's Hospital · USMassachusetts General Hospital · USHarvard University · US
Funding
Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6MSystems Biology of Airway DiseaseP01HL132825 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ZHOU, ANNY XIAOBO · 2016 to 2020
$12.6MMetabolic Control of Stemness in lung epithelial progenitors by FAM13AR01HL127200 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ZHOU, ANNY XIAOBO · 2015 to 2024
$4.9MGenetic and Functional Dissection of a Cluster of COPD GWAS Signals on Chromosome 4qR01HL147148 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CHO, MICHAEL H., SILVERMAN, EDWIN K · 2019 to 2022
$3.5MIdentifying functional variants in COPD GWAS lociR01HL137927 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CHO, MICHAEL H., SILVERMAN, EDWIN K · 2017 to 2020
$3.5MIntegrative Characterization on the function of COPD GWAS gene, HHIPR01HL148667 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WEI, WENYI, ZHOU, ANNY XIAOBO · 2020 to 2023
$2.6MPhysics of bronchial epithelial unjammingR01HL148152 · NHLBI · HARVARD SCHOOL OF PUBLIC HEALTH · PI FREDBERG, JEFFREY J, PARK, JIN-AH · 2019 to 2022
$2.2MIntegrative omics pipeline to identify novel COPD genes and pathwaysK25HL136846 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MORROW, JARRETT · 2017 to 2021
$945kThe role of COPD genetic risk factor HHIP on lymphocytic inflammationK08HL146972 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI YUN, JEONG H · 2020 to 2024
$848kNHLBI NIH HHS K08 HL146972NHLBI NIH HHS P01 HL132825NHLBI NIH HHS R01 HL127200NHLBI NIH HHS R01 HL137927NHLBI NIH HHS R01 HL147148NHLBI NIH HHS R01 HL148152NHLBI NIH HHS R01 HL148667NIEHS NIH HHS P30 ES000002
Abstract
PubMed holds no abstract for this paper.
Indexed as
Gene ExpressionGenetic VariationGenome-Wide Association StudyAlveolar Epithelial CellsDesmoplakinsEpithelial CellsHumansIdiopathic Pulmonary FibrosisDesmoplakinsbronchial epithelial cellscell migrationCRISPR/Cas9 genome-editingDSPrs2076295
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.