ArticlePeerJ2020
Effectiveness of topical antibiotics in treating corals affected by Stony Coral Tissue Loss Disease.
Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 113 citations in OpenAlex.
- What are the toxicity thresholds of chemical pollutants for tropical reef-building corals? A systematic review.Environmental evidence · 2023Pooled it
- Unique Transcriptional Responses by the Sea Anemone Nematostella vectensis to Individual Bacteria: Roles for Bacterial Species, Secreted Products and the Microbiome.Molecular ecology · 2026Article
- Frequent coral disease interventions reduces tissue loss.Scientific reports · 2026Article
- Temperate and filamentous bacteriophages as reservoirs of bacterial virulence in stony coral tissue loss disease.Coral reefs (Online) · 2026Article
- Markers of resilience to stony coral tissue loss disease and putative probiotic functions in the microbiomes of the coral,ISME communications · 2026Article
- Stony Coral Tissue Loss Disease Results in Persistent Microbial-Level Disturbances on Coral Reef Ecosystems.Environmental microbiology reports · 2025Article
- Genotype and symbiont composition rather than environment influence susceptibility to stony coral tissue loss disease in coral restoration broodstock.Scientific reports · 2025Article
- Evaluating the effect of amoxicillin treatment on the microbiome ofApplied and environmental microbiology · 2025Article
- Machine learning reveals distinct gene expression signatures across tissue states in stony coral tissue loss disease.Royal Society open science · 2025Article
- Antibiotic type and dose variably affect microbiomes of a disease-resistant Acropora cervicornis genotype.Environmental microbiome · 2025Article
- Article
- Quorum sensing regulates virulence factors in the coral pathogenApplied and environmental microbiology · 2025Article
- Shifts in the microbiome and virome are associated with stony coral tissue loss disease (SCTLD).ISME communications · 2025Article
- Novel metagenomics analysis of stony coral tissue loss disease.G3 (Bethesda, Md.) · 2024Article
- Novel metagenomics analysis of stony coral tissue loss disease.bioRxiv : the preprint server for biology · 2024Article
- Stony coral tissue loss disease indirectly alters reef communities.Science advances · 2024Article
- Article
- Spatial extent of dysbiosis in the branching coral Pocillopora damicornis during an acute disease outbreak.Scientific reports · 2023Article
- Stony coral tissue loss disease induces transcriptional signatures of in situ degradation of dysfunctional Symbiodiniaceae.Nature communications · 2023Article
- Chemical and genomic characterization of a potential probiotic treatment for stony coral tissue loss disease.Communications biology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since 2014, Stony Coral Tissue Loss Disease (SCTLD) has led to mass mortality of the majority of hard coral species on the Florida Reef Tract. Following the successful treatment of SCTLD lesions on laboratory corals using water dosed with antibiotics, two topical pastes were developed as vehicles to directly apply antibiotic treatments to wild corals. These pastes were tested as placebos and with additions of amoxicillin on active SCTLD lesions on multiple coral species. The effectiveness of the pastes without antibiotics (placebo treatments) was 4% and 9%, no different from untreated controls. Adding amoxicillin to both pastes significantly increased effectiveness to 70% and 84%. Effectiveness with this method was seen across five different coral species, with success rates of the more effective paste ranging from 67% (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.