ArticleThe Pan African medical journal2020
Khat chewing in pregnant women associated with prelabor rupture of membranes, evidence from eastern Ethiopia.
Article in The Pan African medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Magnitude and risk factors of khat, alcohol and cigarettes use among pregnant women in Africa: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2024Pooled it
- Magnitude and associated factors of premature rupture of membranes among pregnant women admitted to a university comprehensive specialized hospital in Central Ethiopia.BMC pregnancy and childbirth · 2026Article
- The Relationship Between Hypertensive Disorders of Pregnancy and PreLabor Rupture of Membranes in Ethiopia: A Systematic Review and Meta-Analysis of Observational Studies.Health science reports · 2026Review
- Risk factors associated with premature rupture of membranes in pregnant women admitted to a tertiary hospital.Medicine · 2026Observational
- Social and Cultural Barriers and Facilitators Affecting Mothers' Dietary Practices in Eastern Ethiopia: A Qualitative Study.Current developments in nutrition · 2025Article
- Article
- Association Between Maternal Undernutrition and Pre-Labor Rupture of Membranes in Ethiopia: A Systematic Review and Meta-Analysis of Observational Studies.Health science reports · 2025Review
- Association between maternal khat use and other determinants and low birth weight in Halaba Zone, South Ethiopia: an unmatched case-control study.Frontiers in pediatrics · 2025Article
- Khat chewing among parents and their children: A potential transgenerational effect.Journal of family medicine and primary care · 2024Article
- Khat use and related determinants among pregnant women within Haramaya, Ethiopia: a mixed methods study.Frontiers in global women's health · 2024Article
- Individual and community-level factors associated with khat (Frontiers in psychiatry · 2024Article
- Determinants of term premature rupture of membrane: case-control study in Saint Paul's Millennium Medical College Hospital, Addis Ababa, Ethiopia.BMC women's health · 2023Article
- The epidemiology of khat (catha edulis) chewing and alcohol consumption among pregnant women in Ethiopia: A systematic review and meta-analysis.PLOS global public health · 2023Article
- Article
- Predictors and perinatal outcomes of pre-labor rupture of membrane among pregnant women admitted to Hiwot Fana Comprehensive Specialized University Hospital, Eastern Ethiopia: a retrospective study.Frontiers in medicine · 2023Article
- Khat chewing and its associated factors among pregnant women in Chiro district, eastern Ethiopia: a community-based study.Frontiers in psychiatry · 2023Article
- Pre-labor rupture of membranes and associated factors among pregnant women admitted to the maternity ward, Northwest Ethiopia.PLOS global public health · 2023Article
- The impact of khat chewing on heart activity and rehabilitation therapy from khat addiction in healthy khat chewers.Scientific reports · 2022Article
- Khat use and associated factors during pregnancy in eastern Ethiopia: A community-based cross-sectional study.Frontiers in global women's health · 2022Article
- Prevalence of premature rupture of membrane and its associated factors among pregnant women in Ethiopia: A systematic review and meta-analysis.SAGE open medicine · 2021Review
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPrelabor rupture of membranes (PROM) is a major factor that affects pregnancy outcome. Results from previous studies have suggested that there is an association between pregnant women, khat chewing and preterm birth, but evidence of association with PROM is sparse. This study therefore aims at identifying association between khat chewing in pregnancy and premature rupture of membranes in eastern Ethiopia.
methodsA health facility-based cross-sectional study was conducted among 1688 pregnant women who came for delivery service in Harar town, Eastern Ethiopia between June to October in 2016. Data were collected using a pre-tested structured questionnaire and checklist to extract data from the medical record. The association between khat and PROM was examined using logistic regression analysis. A statistical significance was declared at p-value < 0.05.
resultsOf the 1688 pregnant women who participated in the study, 397 had prelabor rupture of the membranes, representing a proportion of 23.5% [(95% CI: (21.5, 25.6%)]. Of these 397 prelabor rupture of the membranes 198 (31.53%) were from Khat chewing mothers and, 199(18.77%) were from non-khat chewing mothers. After controlling for potential confounders, the multivariable logistic regression analysis revealed the odds of PROM was 1.51 times higher among khat chewed pregnant women [AOR = 1.51; 95% CI; (1.11, 2.07)] were had no khat chewing.
conclusionThis study found a significant association between khat chewing in pregnancy and PROM. Efforts to reduce PROM need to consider prevention of khat chewing in pregnancy. A specific strategy need to protect pregnant women from khat chewing.
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