Evidence map›Paper›PMID 32550946›Full record

ArticlePrzeglad gastroenterologiczny2020

Survivin expression starts before hepatocellular cancer development in the liver of chronic hepatitis B patients: a pilot, cross-sectional study.

Muhammet Yener Akpinar, Gulcin Guler Simsek, Evrim Kahramanoglu Aksoy, Ferda Pirincci Sapmaz, Selen Kantarci, Metin Uzman, Yasar Nazligul

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Przeglad gastroenterologiczny, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Muhammet Yener AkpinarGastroenterology Department, Kecioren Training and Research Hospital, Ankara, Turkey.
Gulcin Guler SimsekPathology Department Kecioren Training and Research Hospital, Ankara, Turkey.
Evrim Kahramanoglu AksoyGastroenterology Department, Kecioren Training and Research Hospital, Ankara, Turkey.
Ferda Pirincci SapmazGastroenterology Department, Kecioren Training and Research Hospital, Ankara, Turkey.
Selen KantarciInternal Medicine Department, Kecioren Training and Research Hospital, Ankara, Turkey.
Metin UzmanGastroenterology Department, Kecioren Training and Research Hospital, Ankara, Turkey.
Yasar NazligulGastroenterology Department, Kecioren Training and Research Hospital, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSurvivin expression is well known feature of hepatocellular carcinoma (HCC); however, there is no information about survivin expression in chronic hepatitis B (CHB).

aimInvestigating survivin expression in the liver of CHB patients. MATERIAL AND

methodsThis is a single-centre, cross-sectional study. Seventy-five CHB patients and eight control patients were enrolled into the study between 2008 and 2018. Immunohistochemical study was performed by using anti-survivin antibody to evaluate survivin immunoreactivity.

resultsSurvivin immunoreactivity was significantly higher in CHB patients compared to controls (

conclusionsThis is the first study evaluating survivin expression in CHB patients. Understanding the possible relationship between survivin expression and HCC development in this population can promote new studies in terms of new therapies and treatment timing.

Indexed as

apoptosischronic hepatitis Bsurviving

Identifiers

PMID32550946
PMCPMC7294976
OpenAlexW2969708883

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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