Evidence map›Paper›PMID 32550918›Full record

ArticleTheranostics2020

Macrophage correlates with immunophenotype and predicts anti-PD-L1 response of urothelial cancer.

Dongqiang Zeng, Zilan Ye, Jiani Wu, Rui Zhou, Xinxiang Fan, Gaofeng Wang, Yiqiang Huang, Jianhua Wu, Huiying Sun, Miaohong Wang and 5 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed
27.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 187 citations in OpenAlex.

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51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Dongqiang ZengDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, P. R. China.
Zilan YeDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, P. R. China.
Jiani WuDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, P. R. China.
Rui ZhouDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, P. R. China.
Xinxiang FanDepartment of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Gaofeng WangDepartment of Dermatology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Yiqiang HuangDepartment of Urology, Daping Hospital, Army Medical University, Chongqing, P.R. China.
Jianhua WuDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, P. R. China.
Huiying SunDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, P. R. China.
Miaohong WangDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, P. R. China.
Jianping BinDepartment of Cardiology, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yulin LiaoDepartment of Cardiology, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Nailin LiKarolinska Institutet Department of Medicine-Solna, Clinical Pharmacology Group, Karolinska University Hospital-Solna, 171 76, Stockholm, Sweden.
Min ShiDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, P. R. China.
Wangjun LiaoDepartment of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, P. R. China.
Nanfang Hospital · CNSouthern Medical University · CNJohns Hopkins University · USSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune-checkpoint blockades (ICBs) have been routinely implemented to treat metastatic urothelial cancer (mUC), whereas robust biomarkers are urgently warranted. Herein, we explored latent promising biomarkers based on 348 pretreatment mUC samples from IMvigor210.

Indexed as

Antibodies, Monoclonal, HumanizedAntineoplastic Agents, ImmunologicalB7-H1 AntigenBiomarkers, TumorCD8-Positive T-LymphocytesDatabases, GeneticHumansImmunotherapyMacrophagesMutationPrognosisSurvival RateTranscriptomeUrinary Bladder NeoplasmsAntibodies, Monoclonal, HumanizedAntineoplastic Agents, ImmunologicalatezolizumabB7-H1 AntigenBiomarkers, TumorCD274 protein, humanimmune checkpoint blockadeimmunophenotypemacrophageurothelial cancer

Identifiers

PMID32550918
PMCPMC7295060
OpenAlexW3034982015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.