Evidence map›Paper›PMID 32550898›Full record

ArticleTheranostics2020

PEG-coated nanoparticles detachable in acidic microenvironments for the tumor-directed delivery of chemo- and gene therapies for head and neck cancer.

Yu-Li Lo, Chih-Hsien Chang, Chen-Shen Wang, Muh-Hwa Yang, Anya Maan-Yuh Lin, Ci-Jheng Hong, Wei-Hsuan Tseng

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 49 citations in OpenAlex.

  1. EMT and cancer stem cells: Drivers of therapy resistance and promising therapeutic targets.Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2025
    Review
  2. Review
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  5. [Research progress of liposome drug delivery system in the treatment of head and neck cancer].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Review
  6. Review
  7. Review
  8. Review
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  10. Article
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  14. Article
  15. Article
  16. Review
  17. Article
  18. Non-viral vectors for RNA delivery.Journal of controlled release : official journal of the Controlled Release Society · 2022
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yu-Li LoInstitute of Pharmacology, National Yang-Ming University, Taipei 11221, Taiwan.
Chih-Hsien ChangInstitute of Pharmacology, National Yang-Ming University, Taipei 11221, Taiwan.
Chen-Shen WangInstitute of Pharmacology, National Yang-Ming University, Taipei 11221, Taiwan.
Muh-Hwa YangInstitute of Clinical Medicine, National Yang-Ming University, Taipei 11221, Taiwan.
Anya Maan-Yuh LinInstitute of Pharmacology, National Yang-Ming University, Taipei 11221, Taiwan.
Ci-Jheng HongInstitute of Pharmacology, National Yang-Ming University, Taipei 11221, Taiwan.
Wei-Hsuan TsengInstitute of Pharmacology, National Yang-Ming University, Taipei 11221, Taiwan.
National Yang Ming Chiao Tung University · TWNational Yang Ming Chiao Tung University · TWNational Taipei University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AcidsAnimalsApoptosisCarcinoma, Squamous CellCell Line, TumorCell-Penetrating PeptidesDrug Delivery SystemsGenetic TherapyHumansHydrogen-Ion ConcentrationIrinotecanMiceMice, Inbred BALB CMicroRNAsMitochondriaNanoparticlesAcidsCell-Penetrating PeptidesIrinotecanMicroRNAsMIRN200 microRNA, humanPolyethylene GlycolsTopoisomerase I Inhibitorscombinatorial therapyhead and neck cancermicroRNApH-sensitive targeting nanoparticlesself-cleavable PEG-shell

Identifiers

PMID32550898
PMCPMC7295054
OpenAlexW3027905527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.