Evidence map›Paper›PMID 32550892›Full record

ArticleTheranostics2020

Targeting of Formyl Peptide Receptor 2 for

Tamara Boltersdorf, Junaid Ansari, Elena Y Senchenkova, Jieny Groeper, Denise Pajonczyk, Shantel A Vital, Gaganpreet Kaur, J Steve Alexander, Thomas Vogl, Ursula Rescher and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Tamara BoltersdorfDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City, London, W12 0BZ, UK.
Junaid AnsariDepartment of Neurology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA, 71130, USA.
Elena Y SenchenkovaDepartment of Neurology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA, 71130, USA.
Jieny GroeperInstitute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Muenster, D-48149 Muenster, Germany.
Denise PajonczykInstitute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Muenster, D-48149 Muenster, Germany.
Shantel A VitalDepartment of Neurology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA, 71130, USA.
Gaganpreet KaurDepartment of Neurology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA, 71130, USA.
J Steve AlexanderDepartment of Neurology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA, 71130, USA.
Thomas VoglInstitute for Immunology, University of Muenster, D-48149 Muenster, Germany.
Ursula RescherInstitute of Medical Biochemistry, Centre for Molecular Biology of Inflammation, University of Muenster, D-48149 Muenster, Germany.
Nicholas J LongDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City, London, W12 0BZ, UK.
Felicity N E GavinsDepartment of Neurology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA, 71130, USA.
Imperial College London · GBBrunel University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory conditions are associated with a variety of diseases and can significantly contribute to their pathophysiology. Neutrophils are recognised as key players in driving vascular inflammation and promoting inflammation resolution. As a result, neutrophils, and specifically their surface formyl peptide receptors (FPRs), are attractive targets for non-invasive visualization of inflammatory disease states and studying mechanistic details of the process.

Indexed as

Acute DiseaseAdultAgedAnimalsCells, CulturedDisease Models, AnimalFemaleFluorescent DyesHumansIntravital MicroscopyMaleMiceMice, Inbred C57BLMiddle AgedNeutrophilsReceptors, Formyl PeptideFluorescent Dyesformyl peptide receptor 2, mouseReceptors, Formyl PeptideRhodaminesformyl peptide receptorsInflammationintravital microscopyneutrophilssmall-molecule imaging probes

Identifiers

PMID32550892
PMCPMC7295040
OpenAlexW3026763372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.