Evidence map›Paper›PMID 32550738›Full record

ArticleObstetrics & gynecology science2020

Comparison of pain and proper sample status according to usage of tenaculum and analgesia: a randomized clinical trial.

Cihan Comba, Gökhan Demirayak, Sakir Volkan Erdogan, Ibrahim Karaca, Omer Demir, Oguz Guler, Isa Aykut Ozdemir

Registry-linked trialOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Obstetrics & gynecology science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03279666 (A Randomized Controlled Study), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03279666 nacompletednot on this map

A Randomized Controlled Study: Patients' With or Without Tenaculum Placement and Intracervical Blockage/or Not During Colposcopic Biopsy

TypeinterventionalSponsorBakirkoy Dr. Sadi Konuk Research and Training HospitalRan2017 to 2017Enrolled236ConditionsPain Uterus, TenaculumArmsTenaculum replacement
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Impact of HPV Diagnosis and Abnormal Cervical Cytology Results on Sexual Dysfunction and Anxiety.International journal of environmental research and public health · 2023
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Cihan CombaDivision of Gynecologic Oncology, Department of Gynecology and Obstetrics, University of Health Sciences, Sultangazi Haseki Training and Research Hospital, Istanbul, Turkey.
Gökhan DemirayakDivision of Gynecologic Oncology, Department of Gynecology and Obstetrics, University of Health Sciences, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Sakir Volkan ErdoganDepartment of Gynecology and Obstetrics, University of Health Sciences, Bagcilar Training and Research Hospital, Istanbul, Turkey.
Ibrahim KaracaDepartment of Gynecology and Obstetrics, University of Health Sciences, Tepecik Training and Research Hospital, Izmir, Turkey.
Omer DemirDepartment of Gynecology and Obstetrics, Karadeniz Technical University, Trabzon, Turkey.
Oguz GulerDepartment of Gynecology and Obstetrics, Kucukkoy Bilge Hospital, Istanbul, Turkey.
Isa Aykut OzdemirDivision of Gynecologic Oncology, Department of Gynecology and Obstetrics, Medipol University Mega Hospital, Istanbul, Turkey.
Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi · TRHaseki Eğitim ve Araştırma Hastanesi · TRIstanbul Medipol University · TRIzmir University · TRKaradeniz Technical University · TRSağlık Bilimleri Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveColposcopic biopsy is a discomfortable procedure. Additionally, it creates negative influence on sexuality. This study aimed to investigate the relationships among tenaculum, pain perception, and biopsy size during colposcopy.

methodsIn total, 228 patients who underwent colposcopy-directed biopsy were included, and randomized into 4 groups based on whether analgesic and tenaculum were used and replaced (tenaculum with n=58/without analgesic n=56, no tenaculum replacement with n=57/without analgesic n=57). Lidocaine hydrochloride (40 mg) plus adrenaline (0.025 mg) was administered in the analgesic groups. The pain was assessed using a linear visual analog scale. The biopsy specimen size was measured in millimeters.

resultsThe mean age of the patients was 42.85±8.88 years. The most frequent colposcopy indications were atypical squamous cells of undetermined significance and human papilloma virus-positive results on cervical cytology (30.2%; n=69). Low- and high-grade intraepithelial lesions were noted in 14.91% (n=34) and 10.96% (n=25) women through colposcopy-directed biopsy results, respectively. Tenaculum replacement increased pain perception in the without analgesic group; however, no statistically significant differences were noted between of the groups with and without tenaculum replacement with analgesic. The size and number of biopsy specimens were not associated with tenaculum replacement and analgesic use.

conclusionAdministration of analgesics decreased discomfort and pain in patients. Tenaculum replacement aided colposcopists in manipulating the cervix. Additionally, administration of analgesics relieved pain in the tenaculum replacement group.

trial registrationClinicalTrials.gov Identifier: NCT03279666.

Indexed as

BiopsyCervix uteriHuman papilloma virusPain perception

Identifiers

PMID32550738
PMCPMC7393752
OpenAlexW3036523871

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.