Evidence map›Paper›PMID 32550549›Full record

ArticleGene: X2019

Association of

Stefan G J A Camps, Sanne P M Verhoef, Freek G Bouwman, Edwin C M Mariman, Klaas R Westerterp

Open access · hybridAbstract read
In one paragraph

Article in Gene: X, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Genetic variants related to physical activity or sedentary behaviour: a systematic review.The international journal of behavioral nutrition and physical activity · 2021
    Pooled it
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Stefan G J A CampsMaastricht University, Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht (NUTRIM), 6200, MD, Maastricht, the Netherlands.
Sanne P M VerhoefMaastricht University, Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht (NUTRIM), 6200, MD, Maastricht, the Netherlands.
Freek G BouwmanMaastricht University, Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht (NUTRIM), 6200, MD, Maastricht, the Netherlands.
Edwin C M MarimanMaastricht University, Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht (NUTRIM), 6200, MD, Maastricht, the Netherlands.
Klaas R WesterterpMaastricht University, Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht (NUTRIM), 6200, MD, Maastricht, the Netherlands.
Maastricht University · NLNational University Health System · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnergy restriction induces adaptations in resting energy expenditure (REE) and physical activity; inter-individual variability could be ascribed to genetic predisposition.The aim was to examine if changes in REE and physical activity as a result of weight loss were affected by candidate single nucleotide polymorphisms (SNPs).

methods148 subjects (39 men, 109 women), mean ± SD age: 41 ± 9 year; body mass index (BMI): 31.9 ± 3.0 kg/m

resultsThe heterozygotic genotype of

conclusionCarrying the minor

Indexed as

Adaptive thermogenesisADRB2, β2-adrenergic receptorBMI, body mass indexEnergy balanceFFM, fat-free massFM, fat massFTO, fat mass and obesity associatedGenetic predispositionGLM, general linear modellingMC4R, melanocortin 4 receptorMetabolic adaptationPPARD, peroxisome proliferator-activated receptorδPPARGC1A, peroxisome proliferator-activated receptorγ coactivator-1αREEm, resting energy expenditure, measuredREEp, resting energy expenditure, predictedREE, resting energy expenditureSNPs, single nucleotide polymorphismsVLED, very low energy dietWeight loss

Identifiers

PMID32550549
PMCPMC7285957
OpenAlexW2945619598

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.