Evidence map›Paper›PMID 32550264›Full record

ArticleNPJ breast cancer2020

Retinoblastoma protein expression and its predictors in triple-negative breast cancer.

Jaymin M Patel, Andrew Goss, Judy E Garber, Vanda Torous, Edward T Richardson, Miriam J Haviland, Michele R Hacker, Gordon J Freeman, Tessa Nalven, Brian Alexander and 4 more

Open access · goldAbstract read
In one paragraph

Article in NPJ breast cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. A Phase II Study of Abemaciclib for Patients with Retinoblastoma-Positive, Metastatic Triple-Negative Breast Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Targeting TUBG1 in RB1-negative tumors.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  10. Palbociclib as an Antitumor Drug: A License to Kill.Molecules (Basel, Switzerland) · 2024
    Review
  11. Integrative Multiomic Profiling of Triple-Negative Breast Cancer for Identifying Suitable Therapies.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Article
  12. Concurrent RB1 Loss and BRCA Deficiency Predicts Enhanced Immunologic Response and Long-term Survival in Tubo-ovarian High-grade Serous Carcinoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Article
  13. RB1 Genetic Alterations in Estrogen Receptor-Positive Breast Carcinomas: Correlation With Neuroendocrine Differentiation.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2024
    Article
  14. Cancers · 2024
    Article
  15. Article
  16. Concurrent RB1 loss andmedRxiv : the preprint server for health sciences · 2023
    Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Jaymin M PatelDivision of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA USA.ORCID 0000-0001-9945-5555
Andrew GossDivision of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA USA.
Judy E GarberHarvard Medical School, Boston, MA USA.
Vanda TorousHarvard Medical School, Boston, MA USA.
Edward T RichardsonHarvard Medical School, Boston, MA USA.
Miriam J HavilandDepartment of Obstetrics & Gynecology, Beth Israel Deaconess Medical Center, Boston, MA USA.
Michele R HackerDivision of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA USA.
Gordon J FreemanHarvard Medical School, Boston, MA USA.ORCID 0000-0002-7210-5616
Tessa NalvenDivision of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA USA.
Brian AlexanderHarvard Medical School, Boston, MA USA.
Larissa LeeHarvard Medical School, Boston, MA USA.
Laura C CollinsHarvard Medical School, Boston, MA USA.
Stuart J Schnitt *Harvard Medical School, Boston, MA USA.
Nadine Tung *Division of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, MA USA.
Beth Israel Deaconess Medical Center · USHarvard University · USBrigham and Women's Hospital · US

Funding

Tissue and Pathology CoreP50CA168504 · NCI · DANA-FARBER CANCER INST · PI MYLES A BROWN · 2013 to 2026
$30.1M
Role of Tumor Stroma in Therapeutic Response and ResistanceU54CA163125 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI FLAHERTY, KEITH T, FLAHERTY, KEITH T · 2011 to 2015
$4.4M
NCI NIH HHS P50 CA168504NCI NIH HHS U54 CA163125
6 · The paper itself

Abstract

Retinoblastoma protein (Rb) is a product of the

Indexed as

Breast cancerTumour biomarkers

Identifiers

PMID32550264
PMCPMC7275038
OpenAlexW3033978342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.