Evidence map›Paper›PMID 32550192›Full record

ArticleJournal of diabetes and metabolic disorders2020

The regulation of Niemann-Pick C1-Like 1 (NPC1L1) gene expression in opposite direction by

Sara Ahmadi Badi, Atiyyeh Motahhary, Golnaz Bahramali, Morteza Masoumi, Seyedeh Fatemeh Sadati Khalili, Nayereh Ebrahimzadeh, Pegah Nouri, Ayoub Rahimi, Andrea Masotti, Arfa Moshiri and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of diabetes and metabolic disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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  3. Review
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  5. The effect ofJournal of diabetes and metabolic disorders · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Sara Ahmadi Badi *Microbiology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Atiyyeh Motahhary *Microbiology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Golnaz BahramaliDepartment of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, Iran.
Morteza MasoumiMycobacteriology and Pulmonary Research Department, Pasteur Institute of Iran, Tehran, Iran.
Seyedeh Fatemeh Sadati KhaliliMicrobiology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Nayereh EbrahimzadehMycobacteriology and Pulmonary Research Department, Pasteur Institute of Iran, Tehran, Iran.
Pegah NouriMicrobiology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Ayoub RahimiMycobacteriology and Pulmonary Research Department, Pasteur Institute of Iran, Tehran, Iran.
Andrea MasottiBambino Gesù Children's Hospital-IRCCS, Research Laboratories, Rome, Italy.
Arfa MoshiriCancer Department, Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Seyed Davar SiadatMicrobiology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Pasteur Institute of Iran · IRBambino Gesù Children's Hospital · ITIstituto Giannina Gaslini · ITTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe intestine has substantial role in cholesterol homeostasis due to the presence of various cholesterol transporters and gut microbiota.

methodsOMVs were isolated from overnight brain heart infusion (BHI) broth of bacterial standard strains using deoxycholate and assessed by Scanning electron microscopy (SEM). The relative change in genes expression was assessed by Quantitative reverse transcription PCR (RT-qPCR) based on SYBR Green and 2

results

conclusionThe opposite effect of

Indexed as

Bacteroides spp.Cholesterol homeostasisGut microbiotaNiemann-pick C1-like 1Outer membrane vesicles (OMVs)

Identifiers

PMID32550192
PMCPMC7270389
OpenAlexW3020125185

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.