Evidence map›Paper›PMID 32550140›Full record

ArticleQuantitative imaging in medicine and surgery2020

Chest CT study of fifteen COVID-19 patients with positive RT-PCR retest results after discharge.

Chenxi Li, Fan Luo, Liqiu Xie, Yueqin Gao, Na Zhang, Bing Wu

Open access · diamondAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
0.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Is recurrence possible in coronavirus disease 2019 (COVID-19)? Case series and systematic review of literature.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Pooled it
  4. Pooled it
  5. Hospital readmissions and emergency department re-presentation of COVID-19 patients: a systematic review.Revista panamericana de salud publica = Pan American journal of public health · 2022
    Review
  6. Article
  7. Article
  8. Review
  9. Recurrence of SARS-CoV-2 viral RNA in recovered COVID-19 patients: a narrative review.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Review
  10. Article
  11. Article
  12. Making sense of a negative COVID-19 swab test.Quantitative imaging in medicine and surgery · 2020
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Chenxi LiDepartment of Radiology, Public Health Clinical Center of Chengdu, Chengdu, 610000, China.
Fan LuoDepartment of Radiology, Public Health Clinical Center of Chengdu, Chengdu, 610000, China.
Liqiu XieDepartment of Radiology, Public Health Clinical Center of Chengdu, Chengdu, 610000, China.
Yueqin GaoDepartment of Radiology, Public Health Clinical Center of Chengdu, Chengdu, 610000, China.
Na ZhangDepartment of Radiology, Public Health Clinical Center of Chengdu, Chengdu, 610000, China.
Bing WuDepartment of Radiology, China West Hospital, Sichuan University, Chengdu 610041, China.
Public Health Clinical Center of Chengdu · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur hospital is a designated institution for COVID-19 patients in Chengdu, China. This study aimed to analyze the clinical and chest CT features of 15 COVID-19 patients with positive reverse transcription-polymerase chain reaction (RT-PCR) retest results after discharge. Patients who met the current standards of discharge could still carry the SARS-CoV-2 virus.

methodsClinical manifestations, laboratory data, and chest CT images were retrospectively reviewed and analyzed.

resultsThe most common symptoms at Covid-19COVID-19 initial onset were fever (12/15, 80%) and cough (11/15, 73.3%). Most of the patients had a normal white blood cells (12/15, 80%), neutrophils (12/15, 80%), and lymphocytes count (13/15, 86.7%); some patients had increased C-reactive protein (CRP) (5/15, 33.3%), and increased lactate dehydrogenase (LDH) (4/15, 26.7%) during first admission. Five patients (33.3%) had a cough before their first discharge. The average interval from the first discharge to re-admission was 17 days (range, 9-30 days). At re-admission, two (13.3%) patients presented with cough, and one (6.6%) had chest pain with anxiety. At re-admission, all patients had normal clinical results except five (33.3%) patients had increased CRP compared with first discharging, two (13.3%) patients had increased neutrophils count, and one (6.6%) had increased CRP. The majority of patients had normal procalcitonin. Ground glass opacities (GGOs) and reticulation in the peripheral and subpleural areas were the most common CT manifestations, and six patients (40%) showed a transformation from reticulation to GGOs when re-admitted.

conclusionsThere may be no specific clinical characteristics to predict the re-detectability of the virus. A regular medical observation and a bi-monthly follow-up is recommended.

Indexed as

chest computed tomography (chest CT)COVID-19reverse transcription-polymerase chain reaction (RT-PCR)

Identifiers

PMID32550140
PMCPMC7276372
OpenAlexW3026601528

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.