Evidence map›Paper›PMID 32550093›Full record

ArticleCureus2020

Immune Checkpoint Inhibitor-Induced Acute Pancreatitis and Colitis.

Andrea Pagan, Yadis M Arroyo-Martinez, Ankita Tandon, Carlos Bertran-Rodriguez, Jeffrey Gill

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Fatal Immune Checkpoint Inhibitor-related Pancreatitis.Internal medicine (Tokyo, Japan) · 2021
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Andrea PaganInternal Medicine, University of South Florida Morsani College of Medicine, Tampa, USA.
Yadis M Arroyo-MartinezInternal Medicine, University of South Florida, Tampa, USA.
Ankita TandonInternal Medicine, University of South Florida Morsani College of Medicine, Tampa, USA.
Carlos Bertran-RodriguezInternal Medicine, University of South Florida Morsani College of Medicine, Tampa, USA.
Jeffrey GillGastroenterology, James A. Haley Veterans Affairs Hospital, Tampa, USA.
James A. Haley Veterans' Hospital · USUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the promising response of immune checkpoint inhibitors (ICPIs) in treating advanced malignancies, their use in clinical practice is on the rise. ICPIs are associated with a wide spectrum of immune-related adverse events (irAEs). The reported side effects of therapy can be severe enough to require interruption or withdrawal. We are presenting a case of a checkpoint inhibitor-induced acute pancreatitis and colitis, treated with high-dose steroids. This case highlights the need for all physicians to be aware of the different presentations of irAEs from checkpoint inhibitors to provide the correct diagnosis and management.

Indexed as

autoimmune colitisdiarrheaimmune checkpoint inhibitorspancreatitis

Identifiers

PMID32550093
PMCPMC7294850
OpenAlexW3034580922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.