Evidence map›Paper›PMID 32550013›Full record

ArticleNPJ vaccines2020

The vaccinia virus based Sementis Copenhagen Vector vaccine against Zika and chikungunya is immunogenic in non-human primates.

Natalie A Prow, Liang Liu, Mary K McCarthy, Kevin Walters, Raj Kalkeri, Jillian Geiger, Fusataka Koide, Tamara H Cooper, Preethi Eldi, Eri Nakayama and 5 more

Open access · goldAbstract read
In one paragraph

Article in NPJ vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Natalie A Prow *Inflammation Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4029 Australia.
Liang Liu *Experimental Therapeutics Laboratory, School of Pharmacy and Medical Sciences, UniSA Cancer Research Institute, University of South Australia, Adelaide, SA 5000 Australia.
Mary K McCarthy *Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO 80045 USA.
Kevin WaltersDepartment of Infectious Disease Research, Southern Research Institute, Frederick, MD 21701 USA.
Raj KalkeriDepartment of Infectious Disease Research, Southern Research Institute, Frederick, MD 21701 USA.
Jillian GeigerDepartment of Infectious Disease Research, Southern Research Institute, Frederick, MD 21701 USA.
Fusataka KoideDepartment of Infectious Disease Research, Southern Research Institute, Frederick, MD 21701 USA.
Tamara H CooperExperimental Therapeutics Laboratory, School of Pharmacy and Medical Sciences, UniSA Cancer Research Institute, University of South Australia, Adelaide, SA 5000 Australia.
Preethi EldiExperimental Therapeutics Laboratory, School of Pharmacy and Medical Sciences, UniSA Cancer Research Institute, University of South Australia, Adelaide, SA 5000 Australia.
Eri NakayamaInflammation Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4029 Australia.ORCID 0000-0002-0826-3513
Kerrilyn R DienerExperimental Therapeutics Laboratory, School of Pharmacy and Medical Sciences, UniSA Cancer Research Institute, University of South Australia, Adelaide, SA 5000 Australia.
Paul M HowleySementis Ltd, Berwick, VIC 3806 Australia.
John D HayballExperimental Therapeutics Laboratory, School of Pharmacy and Medical Sciences, UniSA Cancer Research Institute, University of South Australia, Adelaide, SA 5000 Australia.
Thomas E MorrisonDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO 80045 USA.
Andreas SuhrbierInflammation Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4029 Australia.
University of South Australia · AUSouthern Research Institute · USQIMR Berghofer Medical Research Institute · AUUniversity of Colorado Denver · USR&G Associates · GB

Funding

Mechanisms of immune suppression during arthritogenic alphavirus infectionsR01AI108725 · NIAID · UNIVERSITY OF COLORADO DENVER · PI MORRISON, THOMAS E · 2014 to 2018
$1.9M
Mechanisms of adaptive immune suppression during pathogenic chikungunya virus infectionF32AI122463 · NIAID · UNIVERSITY OF COLORADO DENVER · PI MCCARTHY, MARY KATHERINE · 2016 to 2018
$174k
NIAID NIH HHS F32 AI122463NIAID NIH HHS HHSN272201000022CNIAID NIH HHS R01 AI108725
6 · The paper itself

Abstract

The Sementis Copenhagen Vector (SCV) is a new vaccinia virus-derived, multiplication-defective, vaccine technology assessed herein in non-human primates. Indian rhesus macaques (

Indexed as

BiotechnologyImmunologyMicrobiology

Identifiers

PMID32550013
PMCPMC7265471
OpenAlexW3034114761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.