Evidence map›Paper›PMID 32549943›Full record

ArticleThe Neurohospitalist2020

Patient-Reported Outcomes (PROs) in Acute Symptomatic Seizure (ASyS) Versus Patients With Established Epilepsy.

Christopher R Newey, Nicolas R Thompson, Pravin George, Vineet Punia, Stephen Hantus, Brittany Lapin, Joao Gomes, Irene Katzan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Neurohospitalist, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Christopher R NeweyEpilepsy Center, Cleveland Clinic, Cleveland, OH, USA.ORCID https://orcid.org/0000-0002-9386-7791
Nicolas R ThompsonNeurological Institute Center for Outcome Research & Evaluation, Cleveland, OH, USA.
Pravin GeorgeCerebrovascular Centers, Cleveland Clinic, Cleveland, OH, USA.
Vineet PuniaEpilepsy Center, Cleveland Clinic, Cleveland, OH, USA.
Stephen HantusEpilepsy Center, Cleveland Clinic, Cleveland, OH, USA.
Brittany LapinNeurological Institute Center for Outcome Research & Evaluation, Cleveland, OH, USA.
Joao GomesCerebrovascular Centers, Cleveland Clinic, Cleveland, OH, USA.
Irene KatzanCerebrovascular Centers, Cleveland Clinic, Cleveland, OH, USA.
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAcute symptomatic seizures (ASyS) are common in critically ill patients. It is unknown how ASyS affect posthospitalization self-reported health compared to patients with established epilepsy.

methodsThis is a retrospective cohort study from 2010 to 2018. Patients were identified by an institutional epilepsy database (Ebase). Patient-reported outcome measures (PROMs) were completed as part of standard of care and included the number of seizures in the prior 4 weeks, Liverpool Seizure Severity Scale (LSSS) ictal score, quality of life in epilepsy (QOLIE)-10, Patient Health Questionnaire-9 scales, and the PROM Information System Global Health (PROMIS-GH) scale. Mixed-effects models were created to adjust for age, sex, and race and to examine score trajectory over the 1 year after baseline.

resultsA total of 15 311 established epilepsy patients and 317 patients with ASyS were identified. When compared to patients with epilepsy, patients with ASyS were older, mostly male, more often black, and had worse baseline scores on the QOLIE-10 (

conclusionCompared to patients with epilepsy, patients with ASyS had fewer seizures but worse epilepsy-specific quality of life. Independent of group status, scores generally improved over time.

Indexed as

acute symptomatic seizurescontinuous electroencephalographycritically illepilepsypatient-reported outcomesseizures

Identifiers

PMID32549943
PMCPMC7271623
OpenAlexW3010061261

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.