Evidence map›Paper›PMID 32549938›Full record

ArticleThe Neurohospitalist2020

Palliative Care in Patients With High-Grade Gliomas in the Neurological Intensive Care Unit.

Jon Rosenberg, Allie Massaro, James Siegler, Stacey Sloate, Matthew Mendlik, Sherman Stein, Joshua Levine

Open access · greenAbstract read
In one paragraph

Article in The Neurohospitalist, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. [S1 guideline on sustainability in intensive care and emergency medicine].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jon RosenbergDepartment of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.ORCID https://orcid.org/0000-0003-1870-9854
Allie MassaroDepartment of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
James SieglerDepartment of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Stacey SloateWharton School of the University of Pennsylvania, Philadelphia, PA, USA.
Matthew MendlikDepartment of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Sherman SteinDied April 2019.
Joshua LevineDepartment of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.ORCID https://orcid.org/0000-0002-2918-4056
Hospital of the University of Pennsylvania · USUniversity of Pennsylvania · US

Funding

The Philadelphia Regional Stroke Trials Network coordinating Center (PRSTNCC)U10NS086474 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI KASNER, SCOTT E · 2013 to 2017
$1.9M
NINDS NIH HHS U10 NS086474
6 · The paper itself

Abstract

backgroundPalliative care improves quality of life in patients with malignancy; however, it may be underutilized in patients with high-grade gliomas (HGGs). We examined the practices regarding palliative care consultation (PCC) in treating patients with HGGs in the neurological intensive care unit (NICU) of an academic medical center.

methodsWe conducted a retrospective cohort study of patients admitted to the NICU from 2011 to 2016 with a previously confirmed histopathological diagnosis of HGG. The primary outcome was the incidence of an inpatient PCC. We also evaluated the impact of PCC on patient care by examining its association with prespecified secondary outcomes of code status amendment to do not resuscitate (DNR), discharge disposition, 30-day mortality, and 30-day readmission rate, length of stay, and place of death.

resultsNinety (36% female) patients with HGGs were identified. Palliative care consultation was obtained in 16 (18%) patients. Palliative care consultation was associated with a greater odds of code status amendment to DNR (odds ratio [OR]: 18.15, 95% confidence interval [CI]: 5.01-65.73), which remained significant after adjustment for confounders (OR: 27.20, 95% CI: 5.49-134.84), a greater odds of discharge to hospice (OR: 24.93, 95% CI: 6.48-95.88), and 30-day mortality (OR: 6.40, 95% CI: 1.96-20.94).

conclusionIn this retrospective study of patients with HGGs admitted to a university-based NICU, PCC was seen in a minority of the sample. Palliative care consultation was associated with code status change to DNR and hospice utilization. Further study is required to determine whether these findings are generalizable and whether interventions that increase PCC utilization are associated with improved quality of life and resource allocation for patients with HGGs.

Indexed as

brain neoplasmsneurocritical careneuro-oncology

Identifiers

PMID32549938
PMCPMC7271613
OpenAlexW2974588471

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.