Evidence map›Paper›PMID 32549754›Full record

ArticleInternational journal of biological sciences2020

KLF10 inhibits cell growth by regulating PTTG1 in multiple myeloma under the regulation of microRNA-106b-5p.

Mimi Zhou, Jinqiu Chen, Hui Zhang, Hailing Liu, Huan Yao, Xiaman Wang, Wanggang Zhang, Yingren Zhao, Nan Yang

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mimi ZhouDepartment of Infectious Diseases, the First Affiliated Hospital of Xi'an Jiaotong University, Yanta West Road No. 277, Xi'an 710061, China.
Jinqiu ChenDepartment of Hematology, the Second Affiliated Hospital of Xi'an Jiaotong University, West Five Road No. 157, Xi'an 710004, China.
Hui ZhangDepartment of Hematology, the Second Affiliated Hospital of Xi'an Jiaotong University, West Five Road No. 157, Xi'an 710004, China.
Hailing LiuDepartment of Hematology, the Second Affiliated Hospital of Xi'an Jiaotong University, West Five Road No. 157, Xi'an 710004, China.
Huan YaoDepartment of Hematology, the Second Affiliated Hospital of Xi'an Jiaotong University, West Five Road No. 157, Xi'an 710004, China.
Xiaman WangDepartment of Hematology, the Second Affiliated Hospital of Xi'an Jiaotong University, West Five Road No. 157, Xi'an 710004, China.
Wanggang ZhangDepartment of Hematology, the Second Affiliated Hospital of Xi'an Jiaotong University, West Five Road No. 157, Xi'an 710004, China.
Yingren ZhaoDepartment of Infectious Diseases, the First Affiliated Hospital of Xi'an Jiaotong University, Yanta West Road No. 277, Xi'an 710061, China.
Nan YangDepartment of Infectious Diseases, the First Affiliated Hospital of Xi'an Jiaotong University, Yanta West Road No. 277, Xi'an 710061, China.
Second Affiliated Hospital of Xi'an Jiaotong University · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Krüppel-like factor 10 (KLF10) has been identified as an important regulator in carcinogenesis and cancer progression. However, the role of KLF10 in multiply myeloma (MM) development and progression remains unknown. In present study, we found that KLF10 mRNA and protein were down-regulated in MM tissues and cell lines. Notably, KLF10 inhibited cell proliferation, cell cycle progression and promoted apoptosis

Indexed as

AnimalsApoptosisCell CycleCell Line, TumorCell ProliferationDown-RegulationEarly Growth Response Transcription FactorsFemaleGene Expression Regulation, NeoplasticHumansKruppel-Like Transcription FactorsMiceMice, NudeMicroRNAsMultiple MyelomaNeoplasms, ExperimentalEarly Growth Response Transcription FactorsKLF10 protein, humanKruppel-Like Transcription FactorsMicroRNAsMIRN106 microRNA, humanpituitary tumor-transforming protein 1, humanSecurinKLF10miR-106b-5pmultiply myelomaproliferationPTTG1

Identifiers

PMID32549754
PMCPMC7294933
OpenAlexW3026854910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.