ReviewJournal of craniovertebral junction & spine
Incidence and risk factors of reoperation in patients with adjacent segment disease: A meta-analysis.
Review in Journal of craniovertebral junction & spine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Association of diffuse idiopathic skeletal hyperostosis with postoperative outcomes following surgery for degenerative lumbar spine disease.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Fusion Construct Length is Associated With Increased Risk of Delayed Reoperation Following Cervical and Lumbar Fusion.Global spine journal · 2026Article
- Biomechanical evaluation of a novel cervical interfacet self-locking cage versus ACDF: a goat cadaveric study combined with human CT-based finite element analysis.BMC musculoskeletal disorders · 2026Article
- Predictors of Interbody Fusion and Adjacent Segment Disease Following Anterior Lumbar Interbody Fusion for Degenerative Pathologies.Journal of clinical medicine · 2026Article
- The Effect of Unilateral Laminotomy Decompression in the Prevention of Adjacent Spinal Canal Stenosis During Lumbar Fusion.Orthopaedic surgery · 2026Article
- Clinical efficacy of 3D-printed guide plates in single-level lumbar degenerative disease: a retrospective comparative study.BMC surgery · 2026Article
- Research on the predictive efficacy of MRI-based endplate bone quality and vertebral body bone quality scores for adjacent segment degeneration after lumbar spinal fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Risk factors and treatment strategies for adjacent segment disease following spinal fusion (Review).Molecular medicine reports · 2025Review
- Development and validation of a predictive model for the risk of symptomatic adjacent segmental degeneration after anterior cervical discectomy and fusion.Frontiers in neurology · 2025Article
- Comparison of Clinical Efficacy in the Treatment of Lumbar Degenerative Disease: Posterior Lumbar Interbody Fusion, Posterior Lumbar Fusion, and Hybrid Surgery.International journal of spine surgery · 2024Article
- Perioperative Complications of Oblique Lumbar Interbody Fusion (OLIF): 5 Years of Experience with OLIF.Asian journal of neurosurgery · 2024Article
- Biomechanical Effects of Different Prosthesis Types and Fixation Ranges in Multisegmental Total En Bloc Spondylectomy: A Finite Element Study.Orthopaedic surgery · 2024Article
- [Correlation of Vertebral Bone Quality and Paraspinal Muscle Changes With Adjacent Segment Degeneration After Transforaminal Lumbar Interbody Fusion Operation].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024Article
- Radiographic Risk Factors for Adjacent Segment Disease Following Anterior Cervical Discectomy and Fusion (ACDF): A Systematic Review and Meta-Analysis.Global spine journal · 2024Review
- Determining a relative total lumbar range of motion to alleviate adjacent segment degeneration after transforaminal lumbar interbody fusion: a finite element analysis.BMC musculoskeletal disorders · 2024Article
- Article
- Exploring the incidence and risk factors of reoperation for symptomatic adjacent segment disease following cervical decompression and fusion.North American Spine Society journal · 2024Article
- Upper instrumented vertebrae selection criteria for degenerative lumbar scoliosis based on the hounsfield unit asymmetry of the first coronal reverse vertebrae: an observational study.Journal of orthopaedic surgery and research · 2023Observational
- Comparative study of outcomes between allograft intervertebral disc transplantation and anterior cervical discectomy and fusion: a retrospective cohort study at least 5 years of follow-up.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designThis was a systematic review of the literature and meta-analysis.
objectiveThe objective of this study was to evaluate the current literature regarding the risk factors contributing to reoperation due to adjacent segment disease (ASD). SUMMARY OF BACKGROUND DATA: ASD is a broad term referring to a variety of complications which might require reoperation. Revision spine surgery is known to be associated with poor clinical outcomes and high rate of complications. Unplanned reoperation has been suggested as a quality marker for the hospitals. MATERIALS AND
methodsAn electronic search was conducted using PubMed. A total of 2467 articles were reviewed. Of these, 55 studies met our inclusion criteria and included an aggregate of 1940 patients. Data were collected pertaining to risk factors including age, sex, fusion length, lumbar lordosis, body mass index, pelvic incidence, sacral slope, pelvis tilt, initial pathology, type of fusion procedure, floating versus sacral or pelvic fusion, presence of preoperative facet or disc degeneration at the junctional segment, and sagittal orientation of the facets at the junctional segment. Analysis of the data was performed using Comprehensive Meta-Analysis software (Biostat, Inc.).
resultsThe overall pooled incidence rate of reoperation due to ASD from all included studies was 0.08 (confidence interval: 0.065-0.098). Meta-regression analysis demonstrated no significant interaction between age and reoperation rate (
conclusionsWe found that 8% of patients in our included studies required reoperation due to ASD. Our analysis also revealed that longer fusion constructs correlated with a higher rate of subsequent revision surgery. Therefore, the surgeon should limit the number of fusion levels if possible to reduce the risk of future reoperation due to ASD. LEVEL OF EVIDENCE: IV.
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