ArticleInternational journal of trichology
Comparison of Serum Level of Sex Hormones in Patients with Frontal Fibrosing Alopecia with Control Group.
Article in International journal of trichology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Hormonal associations in frontal fibrosing alopecia: A systematic review.JAAD international · 2026Article
- Frontal Fibrosing Alopecia and Reproductive Health: Assessing the Role of Sex Hormones in Disease Development.Journal of personalized medicine · 2024Review
- Study of the Thyroid Profile of Patients with Alopecia.Journal of clinical medicine · 2023Review
- Frontal Fibrosing Alopecia: A Review.Journal of clinical medicine · 2021Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextAlthough etiopathogenesis of frontal fibrosing alopecia (FFA) is not fully discovered, it seems that hormonal factors play a role.
aimsThe aim of this study was to investigate the serum level of sex hormones in patients with FFA compared to a control group. SETTINGS AND
designThis was a case-control study. SUBJECTS AND
methodsAll patients who referred to the Dermatology Clinic of Faghihi Hospital, Shiraz University of Medical Sciences, between 2013 and 2018 and were pathologically and clinically diagnosed with FFA were considered as the case group. The control group was selected from community people who did not have alopecia, and each was matched with its counterpart in the case group in terms of gender, age, and menstrual status. Both the groups were evaluated for serum level of sex hormones. STATISTICAL ANALYSIS USED: SPSS software version 23 was used in this study.
resultsOf 20 patients, who were all female, 8 were postmenopausal and 12 were cyclic. There was no significant difference between sex hormone levels of the case and control groups regardless of their menstrual statuses. Similarly, there was no significant difference between hormonal levels in postmenopausal women of both the groups. However, follicle-stimulating hormone (FSH) was significantly lower in the case group cyclic women. Moreover, postmenopausal patients with premenopausal onset of FFA had lower levels of FSH and luteinizing hormone than those with postmenopausal onset. Free testosterone correlated inversely with duration of FFA.
conclusionsIt seems that the pathogenesis of FFA is not associated directly with serum concentrations of sex hormones. Therefore, future studies are recommended to investigate possible tissue mechanisms of hormonal factors involved in its pathogenesis.
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