Evidence map›Paper›PMID 32549386›Full record

ArticleMolecules (Basel, Switzerland)2020

Synthesis, Antimicrobial Activity and Molecular Docking of Novel Thiourea Derivatives Tagged with Thiadiazole, Imidazole and Triazine Moieties as Potential DNA Gyrase and Topoisomerase IV Inhibitors.

Heba E Hashem, Abd El-Galil E Amr, Eman S Nossier, Elsayed A Elsayed, Eman M Azmy

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 85 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Heba E HashemDepartment of Chemistry, Faculty of Women, Ain Shams University, Heliopolis, Cairo 11457, Egypt.ORCID 0000-0002-9324-4404
Abd El-Galil E AmrDrug Exploration & Development Chair (DEDC), Pharmaceutical Chemistry Department, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-1338-706X
Eman S NossierPharmaceutical Medicinal Chemistry Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 11754, Egypt.ORCID 0000-0001-6159-5333
Elsayed A ElsayedBioproducts Research Chair, Zoology Department, Faculty of Science, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-4774-4600
Eman M AzmyDepartment of Chemistry, Faculty of Women, Ain Shams University, Heliopolis, Cairo 11457, Egypt.
Ain Shams University · EGKing Saud University · SAAl-Azhar University · EG

Funding

King Saud University Grant number RGP-1435-047
6 · The paper itself

Abstract

To develop new antimicrobial agents, a series of novel thiourea derivatives incorporated with different moieties

Indexed as

Anti-Bacterial AgentsDNA GyraseDNA Topoisomerase IVEscherichia coliGram-Negative BacteriaGram-Positive BacteriaImidazolesMicrobial Sensitivity TestsMolecular Docking SimulationStructure-Activity RelationshipThiadiazolesThioureaTopoisomerase II InhibitorsTriazinesAnti-Bacterial AgentsDNA GyraseDNA Topoisomerase IVimidazoleImidazolesThiadiazolesThioureaTopoisomerase II InhibitorsTriazinesantimicrobialE. coli DNA B gyraseE. coli Topoisomerase IVmolecular dockingthiourea

Identifiers

PMID32549386
PMCPMC7356696
OpenAlexW3034999189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.